1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethan-1-one

Base Information

• Chemical Name: 1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethan-1-one
• CAS No.: 28924-18-7
• Molecular Formula: C22H19 Br O3
• Molecular Weight: 411.295
• European Community (EC) Number: 249-314-1
• UNII: B8WH676DPH
• DSSTox Substance ID: DTXSID60183126
• Nikkaji Number: J286.483E
• Wikidata: Q83053849
• Mol file: 28924-18-7.mol

Synonyms:28924-18-7;1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethan-1-one;2-Bromo-3',5'-dibenzyloxyacetphenone;1-[3,5-bis(phenylmethoxy)phenyl]-2-bromoethanone;1-[3,5-bis(benzyloxy)phenyl]-2-bromoethanone;EINECS 249-314-1;1-[3,5-BIS(PHENYLMETHOXY)PHENYL]-2-BROMOETHAN-1-ONE;B8WH676DPH;1-(3,5-Bis(benzyloxy)phenyl)-2-bromoethanone;2-bromo-1-[3,5-bis(phenylmethoxy)phenyl]ethanone;C22H19BrO3;1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethanone;Ethanone, 1-(3,5-bis(phenylmethoxy)phenyl)-2-bromo-;UNII-B8WH676DPH;SCHEMBL2451027;C22-H19-Br-O3;DTXSID60183126;BCP31249;AKOS030239841;3',5'-Dibenzyloxy-a-bromoacetophenone;3',5'-Dibenzyloxy-alpha-bromoacetophenone;FT-0663709;A854473;1-(3,5-bis(benzyloxy)phenyl)-2-bromoethan-1-one;2-Bromo-3 inverted exclamation mark ,5 inverted exclamation mark -dibenzyloxyacetphenone

Chemical Property of 1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethan-1-one

Chemical Property:

• Vapor Pressure: 4.56E-11mmHg at 25°C
• Melting Point: 84-86°C
• Boiling Point: 523.8°Cat760mmHg
• Flash Point: 270.6°C
• PSA: 35.53000
• Density: 1.354g/cm³
• LogP: 5.42220
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 410.05176
• Heavy Atom Count: 26
• Complexity: 386

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-3’,5’-dibenzyloxyacetphenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC(=CC(=C2)C(=O)CBr)OCC3=CC=CC=C3

Technology Process of 1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethan-1-one

There total 12 articles about 1-(3,5-Bis(phenylmethoxy)phenyl)-2-bromoethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,5-dibenzyloxyacetophenone (28924-21-2) → 2-bromo-1-[3,5-bis(phenylmethoxy)phenyl]ethanone (28924-18-7)

Guidance literature:

With tetra-N-butylammonium tribromide; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

Reference yield: 96.0%

3,5-bis(benzyloxy)diazoacetophenone (52144-91-9) → 2-bromo-1-[3,5-bis(phenylmethoxy)phenyl]ethanone (28924-18-7)

Guidance literature:

With hydrogen bromide; In methanol; chloroform; at -10 ℃; for 0.166667h;

DOI:10.1002/(SICI)1099-1344(199604)38:4<309::AID-JLCR775>3.0.CO;2-5

Reference yield:

→ 2-bromo-1-[3,5-bis(phenylmethoxy)phenyl]ethanone (28924-18-7) + copper(I) bromide (7787-70-4)

Guidance literature:

upstream raw materials:

3,5-dibenzyloxyacetophenone

3,5-bis(benzyloxy)diazoacetophenone

1-carbomethoxy-3,5-dihydroxybenzene

methyl 3,5-bis(benzyloxy)benzoate

Downstream raw materials:

3,5-dibenzilossi-1-epossietilbenzene

2-bromo-1-(3,5-bis(benzyloxy)phenyl)ethanol

3,5-dibenzyloxyacetophenone

(R)-3’,5’-dibenzyloxyphenylbromohydrin