Technology Process of 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
There total 5 articles about 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
palladium on activated charcoal;
In
tetrahydrofuran;
at -20 - 0 ℃;
for 1.5h;
DOI:10.1021/jo070306p
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 52 percent Turnov. / NaNO2; acetic acid / H2O / 3.5 h / 0 - 20 °C
2: 93 percent / hydrazine hydrate / Pd/C / tetrahydrofuran / 1.5 h / -20 - 0 °C
With
hydrazine hydrate; acetic acid; sodium nitrite;
palladium on activated charcoal;
In
tetrahydrofuran; water;
DOI:10.1021/jo070306p
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 20 percent Turnov. / 15-crown-5; NaNH2 / xylene / 1.5 h / 130 °C
2: 52 percent Turnov. / NaNO2; acetic acid / H2O / 3.5 h / 0 - 20 °C
3: 93 percent / hydrazine hydrate / Pd/C / tetrahydrofuran / 1.5 h / -20 - 0 °C
With
15-crown-5; hydrazine hydrate; sodium amide; acetic acid; sodium nitrite;
palladium on activated charcoal;
In
tetrahydrofuran; water; xylene;
1: Chichibabin reaction;
DOI:10.1021/jo070306p
