Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)-

Base Information

Chemical Name:Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)-
CAS No.:848927-68-4
Molecular Formula:C14H18O5
Molecular Weight:266.294
Hs Code.:
DSSTox Substance ID:DTXSID30479043
Wikidata:Q82312902

Synonyms:848927-68-4;Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)-;SCHEMBL14441556;DTXSID30479043

Suppliers and Price of Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:266.11542367
Heavy Atom Count:19
Complexity:284

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CCC(C(=O)OC)OCC1=CC=CC=C1
Isomeric SMILES:COC(=O)CC[C@@H](C(=O)OC)OCC1=CC=CC=C1

Technology Process of Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)-

There total 3 articles about Pentanedioic acid, 2-(phenylmethoxy)-, dimethyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 55094-97-8
(S)-dimethyl 2-hydroxypentanedioate

: 100-39-0
benzyl bromide

: 848927-68-4
dimethyl (2S)-2-(benzyloxy)pentanedioate

Guidance literature:: With silver(l) oxide; In ethyl acetate; at 20 ℃; for 48h;
DOI:10.1055/s-2004-837199

Reference yield:

: 21461-84-7
(2S)-tetrahydro-5-oxofuran-2-carboxylic acid

: 848927-68-4
dimethyl (2S)-2-(benzyloxy)pentanedioate

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / aq. HCl / 12 h / Heating

2: 79 percent / Ag₂O / ethyl acetate / 48 h / 20 °C

With hydrogenchloride; silver(l) oxide; In ethyl acetate;
DOI:10.1055/s-2004-837199

Reference yield:

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 848927-68-4
dimethyl (2S)-2-(benzyloxy)pentanedioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride; sodium nitrite / water / 18 h / -5 - 20 °C / Inert atmosphere

1.2: 12 h / Inert atmosphere; Reflux

2.1: silver(l) oxide / ethyl acetate / 72 h / 20 °C / Inert atmosphere

With hydrogenchloride; silver(l) oxide; sodium nitrite; In water; ethyl acetate;
DOI:10.1016/j.tetlet.2017.09.008