4,4'-Dimethyldiphenylamine

Base Information

• Chemical Name: 4,4'-Dimethyldiphenylamine
• CAS No.: 620-93-9
• Molecular Formula: C14H15N
• Molecular Weight: 197.28
• Hs Code.: 29214990
• European Community (EC) Number: 210-659-8
• DSSTox Substance ID: DTXSID5060726
• Nikkaji Number: J29.936G
• Wikidata: Q72470228
• Mol file: 620-93-9.mol

Synonyms:4,4'-Dimethyldiphenylamine;620-93-9;Di-p-tolylamine;p,p'-Ditolylamine;4-Methyl-N-(4-methylphenyl)aniline;4,4-Dimethyldiphenylamine;Benzenamine, 4-methyl-N-(4-methylphenyl)-;dip-tolylamine;bis(4-methylphenyl)amine;di-p-tolylamin;Di-p-tolylamine, 97%;EINECS 210-659-8;MFCD00059317;4-Methyl-N-(4-methylphenyl)benzenamine;Di-p-tolyl-amine;n,n-di-p-tolylamine;bis(4-tolyl) amine;N,N-di(p-toluyl)amine;4,4`-Dimethyldiphenylamine;4,4'-dimethyl diphenylamine;SCHEMBL50079;IFLab1_001787;DTXSID5060726;RHPVVNRNAHRJOQ-UHFFFAOYSA-;HMS1417B05;STK291013;AKOS003238511;4-Methyl-N-(4-methylphenyl)aniline #;CS-W015670;GS-3443;NCGC00332045-01;AC-18146;SY005743;AM20060698;D0950;FT-0617072;AB01325793-02;A833581;4,4 inverted exclamation mark -Dimethyldiphenylamine;W-105049;F0486-1801;4,4-dimethyl-N-phenyl-cyclohexa-1,5-dien-1-amine

Chemical Property of 4,4'-Dimethyldiphenylamine

Chemical Property:

• Appearance/Colour: White Powder
• Melting Point: 78-82 °C
• Refractive Index: 1.6095 (estimate)
• Boiling Point: 330.5 °C at 760 mmHg
• PKA: 1.68±0.40(Predicted)
• Flash Point: 167.6 °C
• PSA: 12.03000
• Density: 1.049 g/cm³
• LogP: 4.12000
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Chlorofrm (Slightly), Methanol (Slightly)
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 197.120449483
• Heavy Atom Count: 15
• Complexity: 154

Purity/Quality:

99% ^*data from raw suppliers

p,p'-Ditolylamine >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NC2=CC=C(C=C2)C
• Uses: 4,4''-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.

Technology Process of 4,4'-Dimethyldiphenylamine

There total 112 articles about 4,4'-Dimethyldiphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

1-methylcyclohexan-4-one (589-92-4) → di-p-tolylamine (620-93-9)

Guidance literature:

Reference yield: 99.7%

1N-NaOH + 1-methyl-4-nitrobenzene (99-99-0) + N-(4-methylcyclohexylidene)-4-methylaniline (155269-38-8) → di-p-tolylamine (620-93-9)

Guidance literature:

palladium-carbon; In water; N,N-dimethyl-formamide; benzene;

Reference yield: 99.0%

para-chlorotoluene (106-43-4) + p-toluidine (106-49-0,12221-03-3) → di-p-tolylamine (620-93-9)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); potassium tert-butylate; 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride; In 1,4-dioxane; at 100 ℃; for 1.5h; Inert atmosphere;

DOI:10.3184/030823410X12680525004303

upstream raw materials:

tetrachloromethane

N'-phenyl-N,N-di-p-tolyl-hydrazine

p-cresol

nitroso-di-p-tolyl-amine

Downstream raw materials:

N–methyl–di–p–tolylamine

di-p-tolyl-carbamoyl chloride

tri(p-tolyl)amine

N-phenyl-N',N'-di-p-tolyl-benzamidine

Refernces

• 1、 Kuss-Petermann, Martin,Wenger, Oliver S.. "Electron Transfer Rate Maxima at Large Donor-Acceptor Distances". . p. 1349 - 1358. Retrieved 2016.
• 2、 -. "Diaromatic ring amide compound and application thereof". Paragraph 0101; 0102; 0104-0106. . Retrieved 2021/07/01.
• 3、 Iaroshenko, Viktor O.,Mkrtchyan, Satenik. "Mechanochemical synthesis of aromatic sulfonamides". supporting information. p. 11029 - 11032. Retrieved 2021/11/03.