DIBA-3

Base Information

• Chemical Name: DIBA-3
• CAS No.: 171744-41-5
• Molecular Formula: C18H18N4O4S2
• Molecular Weight: 418.4899
• Mol file: 171744-41-5.mol

Synonyms:

Chemical Property of DIBA-3

Chemical Property:

• Boiling Point: 707.8°Cat760mmHg
• Flash Point: 381.8°C
• Density: 1.47g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIBA-3

There total 4 articles about DIBA-3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

acetic anhydride (108-24-7) + 2,2'-Dithiobis(5-aminobenzamide) (177785-53-4) → 2,2'-Dithiobis(5-acetylamino)benzamide (171744-41-5)

Guidance literature:

With acetic acid; at 100 ℃; for 4h;

DOI:10.1016/S0968-0896(96)00269-6

Reference yield:

2,2'-Dithiobis(5-aminobenzamide) (177785-53-4) → 2,2'-Dithiobis(5-acetylamino)benzamide (171744-41-5)

Guidance literature:

With acetic anhydride; dimethyl sulfoxide; In water; acetic acid;

Reference yield:

2-chloro-5-nitro-benzamide (16588-15-1) → 2,2'-Dithiobis(5-acetylamino)benzamide (171744-41-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 21 percent / Na₂S*9H₂O, S / ethanol / 1 h / Heating

2: 48 percent / Fe, aq. AcOH / 2 h / Heating

3: 59 percent / acetic acid / 4 h / 100 °C

With sodium sulfide; iron; acetic acid; In ethanol;

DOI:10.1016/S0968-0896(96)00269-6

upstream raw materials:

acetic anhydride

2,2'-Dithiobis(5-aminobenzamide)

2-chloro-5-nitro-benzamide

2,2'-dithiobis-5-nitrobenzamide

Refernces

• 1、 Domagala, John M.,Bader, John P.,Gogliotti, Rocco D.,Sanchez, Joseph P.,Stier, Michael A.,Song, Yuntao,Vara Prasad,Tummino, Peter J.,Scholten, Jeffrey,Harvey, Patricia,Holler, Tod,Gracheck, Steve,Hupe, Donald,Rice, William G.,Schultz, Robert. "A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: The 2,2'-dithiobisbenzamides". . p. 569 - 579. Retrieved 2007/10/03.
• 2、 -. "Arylthio compounds". . . Retrieved 2008/06/13.