6-Azaspiro[2.5]octane-5,7-dione

Base Information

Chemical Name:6-Azaspiro[2.5]octane-5,7-dione
CAS No.:1194-45-2
Molecular Formula:C7H9 N O2
Molecular Weight:139.154
Hs Code.:
European Community (EC) Number:869-705-6
DSSTox Substance ID:DTXSID10701551
Wikidata:Q82633256
Mol file:1194-45-2.mol

Synonyms:6-Azaspiro[2.5]octane-5,7-dione;1194-45-2;SCHEMBL19585725;DTXSID10701551;BAA19445;CS-0077344;EN300-3202520;Z1262692566

Suppliers and Price of 6-Azaspiro[2.5]octane-5,7-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Azaspiro[2.5]octane-5,7-dione 95+%
1g
$ 1148.00

Chemenu
6-Azaspiro[2.5]octane-5,7-dione 95%
1g
$ 1082.00

Alichem
6-Azaspiro[2.5]octane-5,7-dione
1g
$ 1351.98

Alichem
6-Azaspiro[2.5]octane-5,7-dione
250mg
$ 482.13

AK Scientific
6-Azaspiro[2.5]octane-5,7-dione
2.5g
$ 1535.00

AK Scientific
6-Azaspiro[2.5]octane-5,7-dione
1g
$ 831.00

Total 7 raw suppliers

Chemical Property of 6-Azaspiro[2.5]octane-5,7-dione

Chemical Property:

Melting Point:165 °C
Boiling Point:333.6±11.0 °C(Predicted)
PSA：49.66000
Density:1.27±0.1 g/cm3(Predicted)
LogP:0.47910
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:139.063328530
Heavy Atom Count:10
Complexity:188

Purity/Quality:

NLT 98% ^*data from raw suppliers

6-Azaspiro[2.5]octane-5,7-dione 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC12CC(=O)NC(=O)C2

Technology Process of 6-Azaspiro[2.5]octane-5,7-dione

There total 5 articles about 6-Azaspiro[2.5]octane-5,7-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70197-77-2
(1-carboxymethylcyclopropyl)acetic acid

: 1194-45-2
6-azaspiro[2.5]octane-5,7-dione

Guidance literature:: With urea; at 175 ℃; for 1h;

Reference yield:

: 136476-38-5
cyclopropane-1,1-diylbis(methylene) dimethanesulfonate

: 1194-45-2
6-azaspiro[2.5]octane-5,7-dione

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 5 h / 20 - 100 °C

2: water; sodium hydroxide / methanol / 4 h / Reflux

3: urea / 1 h / 175 °C

With water; urea; sodium hydroxide; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 20778-47-6
(1-cyanomethyl-cyclopropyl)-acetonitrile

: 1194-45-2
6-azaspiro[2.5]octane-5,7-dione

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / methanol / 4 h / Reflux

2: urea / 1 h / 175 °C

With water; urea; sodium hydroxide; In methanol;