1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester

Base Information

Chemical Name:1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester
CAS No.:79759-36-7
Molecular Formula:C17H15ClN2O3
Molecular Weight:330.7656
Hs Code.:
DSSTox Substance ID:DTXSID30229863
Wikidata:Q83110228

Synonyms:BRN 5612072;79759-36-7;1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester;Ethyl 2,3-dihydro-5-chloro-2-oxo-3-phenyl-1H-benzimidazole-1-acetate;Ethyl (5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)acetate;DTXSID30229863;LS-32590

Suppliers and Price of 1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester

Chemical Property:

Vapor Pressure:2.41E-09mmHg at 25°C
Boiling Point:479.2°Cat760mmHg
Flash Point:243.6°C
Density:1.337g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:330.0771200
Heavy Atom Count:23
Complexity:453

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CN1C2=C(C=C(C=C2)Cl)N(C1=O)C3=CC=CC=C3

Technology Process of 1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester

There total 3 articles about 1H-Benzimidazole-1-acetic acid, 2,3-dihydro-5-chloro-2-oxo-3-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 54986-47-9
6-chloro-1,3-dihydro-1-phenyl-2H-benzimidazol-2-one

: 623-48-3
ethyl iodoacetae

: 79759-36-7
(5-Chloro-2-oxo-3-phenyl-2,3-dihydro-benzoimidazol-1-yl)-acetic acid ethyl ester

Guidance literature:: With sodium hydroxide; In methanol; for 5h; Heating;

Reference yield:

: 68406-47-3
4-chloro-N₂-phenylbenzene-1,2-diamine

: 79759-36-7
(5-Chloro-2-oxo-3-phenyl-2,3-dihydro-benzoimidazol-1-yl)-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / CHCl₃ / 20 h / Heating

2: 99.3 percent / EtONa / ethanol / 3 h / Heating

3: 34 percent / NaOH / methanol / 5 h / Heating

With sodium hydroxide; sodium ethanolate; In methanol; ethanol; chloroform;

Reference yield:

: 79759-11-8
N¹-phenyl-N²-carbethoxy-5-chloro-o.phenylenediamine

: 79759-36-7
(5-Chloro-2-oxo-3-phenyl-2,3-dihydro-benzoimidazol-1-yl)-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 99.3 percent / EtONa / ethanol / 3 h / Heating

2: 34 percent / NaOH / methanol / 5 h / Heating

With sodium hydroxide; sodium ethanolate; In methanol; ethanol;