ME-143

Base Information

Chemical Name:ME-143
CAS No.:852536-39-1
Molecular Formula:C21H18O4
Molecular Weight:334.36500
Hs Code.:
Mol file:852536-39-1.mol

Synonyms:3-(4-hydroxy-phenyl)-2-phenyl-thiazolidin-4-one;4-Thiazolidinone,3-(4-hydroxyphenyl)-2-phenyl;3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)chroman-7-ol;

Suppliers and Price of ME-143

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of ME-143

Chemical Property:

Boiling Point:536.3±50.0 °C(Predicted)
PKA:9.89±0.60(Predicted)
PSA：69.92000
Density:1.332±0.06 g/cm3(Predicted)
LogP:4.11150

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ME-143

There total 7 articles about ME-143 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 852536-35-7,1213777-80-0
3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)chroman-7-ol

: 852536-39-1
3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)chroman-7-ol

Guidance literature:: 3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)chroman-7-ol; With boron tribromide; In chloroform; Reflux;

With water; sodium hydroxide; In chloroform; pH=>= 12;

With hydrogenchloride; In water; ethyl acetate; pH=5.5 - 6.5;

Reference yield:

: 17238-05-0,37054-07-2,58865-02-4
dihydrodaidzein

: 852536-39-1
3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)chroman-7-ol

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide

2.1: magnesium / tetrahydrofuran; ethylene dibromide / 0.75 h / 35 °C

3.1: hydrogen / palladium/alumina / tetrahydrofuran

4.1: water; potassium fluoride / tetrahydrofuran / Reflux

5.1: boron tribromide / chloroform / Reflux

5.2: pH >= 12

5.3: pH 5.5 - 6.5

With 1H-imidazole; potassium fluoride; water; hydrogen; boron tribromide; magnesium; palladium/alumina; In tetrahydrofuran; chloroform; ethylene dibromide; N,N-dimethyl-formamide;

Reference yield:

: 1374639-48-1
7,4'-di(tert-butyldimethylsilyl)oxy-4-(4-methoxyphenyl)-isoflav-3-ene

: 852536-39-1
3-(4-hydroxyphenyl)-4-(4-hydroxyphenyl)chroman-7-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen / palladium/alumina / tetrahydrofuran

2.1: water; potassium fluoride / tetrahydrofuran / Reflux

3.1: boron tribromide / chloroform / Reflux

3.2: pH >= 12

3.3: pH 5.5 - 6.5

With potassium fluoride; water; hydrogen; boron tribromide; palladium/alumina; In tetrahydrofuran; chloroform;