Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)-

Base Information

Chemical Name:Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)-
CAS No.:85370-88-3
Molecular Formula:C17H31NOSi2
Molecular Weight:321.61
Hs Code.:
DSSTox Substance ID:DTXSID00455197
Wikidata:Q82277107

Synonyms:Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)-;85370-88-3;DTXSID00455197

Suppliers and Price of Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)-

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:321.19441768
Heavy Atom Count:21
Complexity:331

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=C(C=CC=C1[Si](C)(C)C)[Si](C)(C)C

Technology Process of Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)-

There total 3 articles about Benzamide, N,N-diethyl-2,6-bis(trimethylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 75-77-4
chloro-trimethyl-silane

: 62924-92-9
N,N-diethyl-2-(trimethylsilyl)benzamide

: 85370-88-3
N,N-diethyl-2,6-bis(trimethylsilyl)benzamide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; pentane; at -78 - 20 ℃; for 5h; Inert atmosphere;
DOI:10.1021/acs.joc.9b02014

Reference yield: 90.0%

: 75-77-4
chloro-trimethyl-silane

: 1696-17-9
N,N-diethylbenzamide

: 85370-88-3
N,N-diethyl-2,6-bis(trimethylsilyl)benzamide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; at -78 ℃;
DOI:10.1016/S0040-4039(00)98418-1

Reference yield:

: 1696-17-9
N,N-diethylbenzamide

: 85370-88-3
N,N-diethyl-2,6-bis(trimethylsilyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / tetrahydrofuran; pentane / 5 h / -78 - 20 °C / Inert atmosphere

2: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / tetrahydrofuran; pentane / 5 h / -78 - 20 °C / Inert atmosphere

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; pentane;
DOI:10.1021/acs.joc.9b02014