Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]-

Base Information

Chemical Name:Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]-
CAS No.:856906-43-9
Molecular Formula:C15H13BrO2
Molecular Weight:305.171
Hs Code.:
DSSTox Substance ID:DTXSID80465577
Wikidata:Q82291630

Synonyms:Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]-;856906-43-9;SCHEMBL12921043;DTXSID80465577

Suppliers and Price of Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]-

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:304.00989
Heavy Atom Count:18
Complexity:274

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=C(C(=CC=C1)OCC2=CC=CC=C2)Br

Technology Process of Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]-

There total 5 articles about Ethanone, 1-[2-bromo-3-(phenylmethoxy)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 75-16-1
methylmagnesium bromide

: 158584-99-7
3-(benzyloxy)-2-bromobenzaldehyde

: 856906-43-9
1-(3-(benzyloxy)-2-bromophenyl)ethan-1-one

Guidance literature:: methylmagnesium bromide; 3-(benzyloxy)-2-bromobenzaldehyde; In tetrahydrofuran; diethyl ether; at -5 ℃; for 1h; Inert atmosphere;

With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; sodium bromide; In tetrahydrofuran; at 0 ℃; for 1.5h; Inert atmosphere;

Reference yield:

: 870288-28-1
1-(3-benzyloxy-2-bromo-phenyl)-ethanol

: 856906-43-9
1-(3-(benzyloxy)-2-bromophenyl)ethan-1-one

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; sodium bromide; In tetrahydrofuran; at 0 ℃; for 1.5h;
DOI:10.1021/ja052151d

Reference yield:

: 158584-99-7
3-(benzyloxy)-2-bromobenzaldehyde

: 856906-43-9
1-(3-(benzyloxy)-2-bromophenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 1 h / -5 °C

2: 8.08 g / TEMPO; aq. NaClO; NaHCO₃ / NaBr / tetrahydrofuran / 1.5 h / 0 °C

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; sodium bromide; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja052151d