2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol

Base Information

Chemical Name:2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol
CAS No.:86129-52-4
Molecular Formula:C11H16ClNO
Molecular Weight:213.707
Hs Code.:
DSSTox Substance ID:DTXSID30538482
Wikidata:Q82413893

Synonyms:86129-52-4;2-[[2-(2-chlorophenyl)-ethyl]methylamino]ethanol;2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol;SCHEMBL10866447;DTXSID30538482;NNMMCSFNUJXNIX-UHFFFAOYSA-N;2-[[2-(2-chlorophenyl)ethyl]methylamino]ethanol;2-[[2-(2-chlorophenyl)-ethyl]-methylamino]ethanol

Suppliers and Price of 2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:213.0920418
Heavy Atom Count:14
Complexity:154

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(CCC1=CC=CC=C1Cl)CCO

Technology Process of 2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol

There total 3 articles about 2-{[2-(2-Chlorophenyl)ethyl](methyl)amino}ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 86129-51-3
2-(2-chlorophenyl)-N-(2-hydroxyethyl)-N-methyl-acetamide

: 86129-52-4
2-[[2-(2-chlorophenyl)ethyl](methyl)amino]ethanol

Guidance literature:: With borane-THF; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1016/j.bmc.2007.12.009

Reference yield:

: 51512-09-5
2-(2-chlorophenyl)acetyl chloride

: 86129-52-4
2-[[2-(2-chlorophenyl)ethyl](methyl)amino]ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / CH₂Cl₂

2: B₂H₆ / tetrahydrofuran

With diborane; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00363a001

Reference yield:

: 2444-36-2
2'-chloro-benzeneacetic acid

: 86129-52-4
2-[[2-(2-chlorophenyl)ethyl](methyl)amino]ethanol

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / SOCl₂, DMF / toluene

2: 80 percent / CH₂Cl₂

3: B₂H₆ / tetrahydrofuran

With thionyl chloride; N,N-dimethyl-formamide; diborane; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/jm00363a001