4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione

Base Information

Chemical Name:4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione
CAS No.:86212-51-3
Molecular Formula:C₁₅H₁₁N₃S
Molecular Weight:265.338
Hs Code.:
DSSTox Substance ID:DTXSID90522807
Wikidata:Q82388411

Synonyms:86212-51-3;4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione;SCHEMBL22357053;DTXSID90522807;phenyl-6-(pyridin-2-yl)pyrimidin-2-thiol

Suppliers and Price of 4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:265.06736854
Heavy Atom Count:19
Complexity:408

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=S)NC(=C2)C3=CC=CC=N3

Technology Process of 4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione

There total 1 articles about 4-Phenyl-6-(pyridin-2-yl)pyrimidine-2(1H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5337-53-1
3-phenyl-1-(2-pyridyl)prop-2-en-1-one

: 86212-51-3
6-phenyl-4-pyridin-2-yl-1H-pyrimidine-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / aq. H₂O₂; NaOH / acetone; methanol / 10 - 15 °C

2: 80 percent / NaOH / ethanol / 2 h / Heating

With sodium hydroxide; dihydrogen peroxide; In methanol; ethanol; acetone;

Reference yield: 75.0%

: 86212-51-3
6-phenyl-4-pyridin-2-yl-1H-pyrimidine-2-thione

: 74-88-4
methyl iodide

: 928006-68-2
2-methylsulfanyl-4-phenyl-6-pyridin-2-yl-pyrimidine

Guidance literature:: 6-phenyl-4-pyridin-2-yl-1H-pyrimidine-2-thione; With potassium hydroxide; In ethanol; for 0.5h; Heating;

methyl iodide; In ethanol; for 6h; Heating;

Reference yield:

: 86212-51-3
6-phenyl-4-pyridin-2-yl-1H-pyrimidine-2-thione

: 928006-76-2
5-phenyl7-pyridin-2-yl-2H-[1,2,4]trizolo[4,3-a]pyrimidin-3-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide / ethanol / 0.5 h / Heating

1.2: 75 percent / ethanol / 6 h / Heating

2.1: 70 percent / hydrazine hydrate / 5 h / Heating

3.1: 70 percent / NaOEt / ethanol / 0.5 h / 20 °C

With potassium hydroxide; sodium ethanolate; hydrazine hydrate; In ethanol;