5-Ethynyl-2,4-dimethylpyrimidine

Base Information

Chemical Name:5-Ethynyl-2,4-dimethylpyrimidine
CAS No.:86521-01-9
Molecular Formula:C8H8N2
Molecular Weight:132.165
Hs Code.:2933599090
DSSTox Substance ID:DTXSID30517611
Wikidata:Q82379725
Mol file:86521-01-9.mol

Synonyms:5-Ethynyl-2,4-dimethylpyrimidine;86521-01-9;DTXSID30517611

Suppliers and Price of 5-Ethynyl-2,4-dimethylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-Ethynyl-2,4-dimethylpyrimidine

Chemical Property:

Melting Point:66-67.5 °C
Boiling Point:206.9±28.0 °C(Predicted)
PKA:1.18±0.29(Predicted)
PSA：25.78000
Density:1.05±0.1 g/cm3(Predicted)
LogP:1.07470
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:132.068748264
Heavy Atom Count:10
Complexity:156

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=NC=C1C#C)C

Technology Process of 5-Ethynyl-2,4-dimethylpyrimidine

There total 2 articles about 5-Ethynyl-2,4-dimethylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 86521-16-6
2,4-Dimethyl-5-trimethylsilanylethynyl-pyrimidine

: 86521-01-9
5-ethynyl-2,4-dimethylpyrimidine

Guidance literature:: With potassium hydroxide; In methanol; for 1h; Ambient temperature;
DOI:10.1055/s-1983-30319

Reference yield:

: 69696-37-3
5-bromo-2,4-dimethylpyrimidine

: 86521-01-9
5-ethynyl-2,4-dimethylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / bispalladium dichloride, copper(I) iodide, triethylamine / 6 h / 100 °C

2: 77 percent / aq. KOH / methanol / 1 h / Ambient temperature

With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; triethylamine; In methanol;
DOI:10.1055/s-1983-30319