69696-37-3

Usage

Uses

Used in Organic Synthesis:
5-Bromo-2,4-dimethylpyrimidine is used as a building block in organic synthesis for the creation of various biologically active compounds. Its unique structure allows for the development of new molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In pharmaceutical research, 5-bromo-2,4-dimethylpyrimidine serves as a key intermediate for the synthesis of drugs with therapeutic properties. Its versatility in chemical reactions enables the production of a wide range of pharmaceutical agents.
Used in Agrochemicals:
5-Bromo-2,4-dimethylpyrimidine is also utilized as a precursor in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Specialty Chemicals:
5-broMo-2,4-diMethyl-pyriMidine finds application in the production of specialty chemicals, which are tailored for specific industries and applications, such as dyes, coatings, and advanced materials. Its unique properties make it a valuable component in these specialized chemical formulations.

Upstream product

• 69696-36-2 5-bromo-4-hydrazinyl-2,6-dimethylpyrimidine 
• 6622-92-0 4-hydroxy 2,6-dimethylpyrimidine 
• 858269-28-0 5-bromo-2,6-dimethylpyrimidin-4-ol 
• 69696-35-1 5-bromo-4-chloro-2,6-dimethylpyrimidine 

Downstream Products

• 127588-22-1 2,4-dimethyl-5-phenylpyrimidine 
• 1445787-52-9 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)-8-fluoroquinolin-4-yl)amino)-5-cyclopentylbenzoic acid 
• 1445790-97-5 methyl 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)-8-fluoroquinolin-4-yl)amino)-5-cyclopentylbenzate 
• 1445787-42-7 3-((3-carbamoyl-7-(2,4-dimethylpyrimidin-5-yl)quinolin-4-yl)amino)-5-isopropoxybenzoic acid 
• 1445787-44-9 3-((7-(2,4-dimethylpyrimidin-5-yl)-3-sulfamoylquinolin-4-yl)amino)-5-isopropoxybenzoic acid 
• 1951411-46-3 2,4-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine 
• 2170605-42-0 (2,4-dimethylpyrimidin-5-yl)boronic acid 
• 86521-01-9 5-ethynyl-2,4-dimethylpyrimidine 

Relevant academic research and scientific papers

TRIAZOLOPYRIDINE COMPOUNDS AND USES THEREOF

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R6, R7 and R8 are as defined herein.

IMIDAZOPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R3, R4, R6, and R7 are as defined herein.

TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

CHEMICAL COMPOUNDS

The invention is directed to substituted quinoline derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R1, R2, R3; R4; and R5 are defined herein. The compounds of the invention are inhibitors of lactate dehydrogenase A and can be useful in the treatment of cancer and diseases associated with tumor cell metabolism, such as cancer, and more specifically cancers of the breast, colon, prostate and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting lactate dehydrogenase A activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.