N'-Benzoyl-N,N'-dimethylbenzohydrazide

Base Information

• Chemical Name: N'-Benzoyl-N,N'-dimethylbenzohydrazide
• CAS No.: 1226-43-3
• Molecular Formula: C16H16N2O2
• Molecular Weight: 268.315
• Hs Code.: 2928000090
• European Community (EC) Number: 214-961-0
• NSC Number: 58886
• DSSTox Substance ID: DTXSID8061632
• Nikkaji Number: J129.050I
• Wikidata: Q81989575
• ChEMBL ID: CHEMBL2286715
• Mol file: 1226-43-3.mol

Synonyms:N'-Benzoyl-N,N'-dimethylbenzohydrazide;1226-43-3;1,2-Dibenzoyl-1,2-dimethylhydrazine;Benzoic acid, 2-benzoyl-1,2-dimethylhydrazide;2'-Benzoyl-1',2'-dimethylbenzohydrazide;Hydrazine, 1,2-dibenzoyl-1,2-dimethyl-;CHEMBL2286715;EINECS 214-961-0;NSC 58886;BENZOIC 2-BENZOYL-1,2-DIMETHYLHYDRAZIDE;N,N'-dimethyl-N'-(phenylcarbonyl)benzohydrazide;NSC58886;NCIOpen2_002311;Benzoic acid,2-dimethylhydrazide;DTXSID8061632;SCHEMBL11211866;AMY25103;BDBM50488518;MFCD00020672;NSC-58886;STK330522;Hydrazine,2-dibenzoyl-1,2-dimethyl-;AKOS005438425;N'-benzoyl-N,N'-dimethyl-benzohydrazide;NCGC00325074-01;LS-05887;N'-Benzoyl-N,N'-dimethylbenzohydrazide #;N/'-Benzoyl-N,N/'-dimethylbenzohydrazide;CS-0318691;FT-0655796;AB01319942-02;A804939;sodium ethyl 2-(8-ethyl-3,4-dihydro-1H-pyrano[3,4-b]indol-9-id-1-yl)acetate;N'-benzoyl-N,N'-dimethylbenzohydrazide

Chemical Property of N'-Benzoyl-N,N'-dimethylbenzohydrazide

Chemical Property:

• Vapor Pressure: 3.36E-06mmHg at 25°C
• Melting Point: 78-84 °C(lit.)
• Refractive Index: 1.599
• Boiling Point: 387.2 °C at 760 mmHg
• Flash Point: 161.5 °C
• PSA: 40.62000
• Density: 1.177 g/cm³
• LogP: 2.44580
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 268.121177757
• Heavy Atom Count: 20
• Complexity: 310

Purity/Quality:

97% ^*data from raw suppliers

N'-Benzoyl-N,N'-dimethylbenzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C(=O)C1=CC=CC=C1)N(C)C(=O)C2=CC=CC=C2

Technology Process of N'-Benzoyl-N,N'-dimethylbenzohydrazide

There total 9 articles about N'-Benzoyl-N,N'-dimethylbenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1,2-Dimethyl-3,5-diphenylpyrazolium-4-olat (35229-03-9) → N'-benzoyl-N,N'-dimethylbenzohydrazide (1226-43-3)

Guidance literature:

With 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodofluorescein disodium salt; oxygen; In methanol; toluene; at 5 ℃; for 16h; Irradiation;

Reference yield: 85.0%

N,N'-Dimethylhydrazine dihydrochloride (306-37-6) + benzoyl chloride (98-88-4) → N'-benzoyl-N,N'-dimethylbenzohydrazide (1226-43-3)

Guidance literature:

N,N'-Dimethylhydrazine dihydrochloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 0.333333h;

benzoyl chloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/acs.orglett.1c00834

Reference yield: 77.0%

C44H82N6Sc2 + benzoyl chloride (98-88-4) → N'-benzoyl-N,N'-dimethylbenzohydrazide (1226-43-3) + C42H76Cl2N4Sc2

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 8h; Inert atmosphere; Glovebox;

DOI:10.1021/jacs.9b04293

upstream raw materials:

benzoyl chloride

N,N-Dimethylhydrazine

N'-benzoylbenzohydrazide

dimethyl sulfate

Downstream raw materials:

1,2-dimethyl-1,2-di(thiobenzoyl)hydrazine

1,2-dibenzyl-1,2-dimethylhydrazine