7-phenylmethoxy-2H-triazolo[4,5-d]pyrimidin-5-amine

Base Information

• Chemical Name: 7-phenylmethoxy-2H-triazolo[4,5-d]pyrimidin-5-amine
• CAS No.: 6301-83-3
• Molecular Formula: C11H10 N6 O
• Molecular Weight: 242.2367
• NSC Number: 42713
• DSSTox Substance ID: DTXSID90423527
• Nikkaji Number: J634.530A
• Wikidata: Q82235763
• Pharos Ligand ID: DVMYW6G9QWBN
• ChEMBL ID: CHEMBL333928

Synonyms:CHEMBL333928;6301-83-3;7-(benzyloxy)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine;7-phenylmethoxy-2H-triazolo[4,5-d]pyrimidin-5-amine;SCHEMBL3259848;DTXSID90423527;ZHTBAYPUCDCQPX-UHFFFAOYSA-N;NSC42713;BDBM50106515;NSC-42713;F81320;7-(Phenylmethoxy)-1H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine;7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamine;7-(BENZYLOXY)-2H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE;AEY

Chemical Property of 7-phenylmethoxy-2H-triazolo[4,5-d]pyrimidin-5-amine

Chemical Property:

• Vapor Pressure: 2.21E-06mmHg at 25°C
• Boiling Point: 392.9°Cat760mmHg
• Flash Point: 191.4°C
• Density: 1.6g/cm³
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 242.09160896
• Heavy Atom Count: 18
• Complexity: 272

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=NC(=NC3=NNN=C32)N

Technology Process of 7-phenylmethoxy-2H-triazolo[4,5-d]pyrimidin-5-amine

There total 3 articles about 7-phenylmethoxy-2H-triazolo[4,5-d]pyrimidin-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2,4,5-triamino-6-benzyloxy-pyrimidine (19916-72-4) → 7-(benzyloxy)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (6301-83-3)

Guidance literature:

With isopentyl nitrite; In dimethyl sulfoxide; at 20 ℃; Inert atmosphere;

DOI:10.1039/c7md00268h

Reference yield:

(E)-6-(benzyloxy)-5-((4-chlorophenyl)diazenyl)pyrimidine-2,4-diamine → 7-(benzyloxy)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (6301-83-3)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc; acetic acid / ethanol / 2 h / 70 °C / Inert atmosphere

2: isopentyl nitrite / dimethyl sulfoxide / 20 °C / Inert atmosphere

With acetic acid; zinc; isopentyl nitrite; In ethanol; dimethyl sulfoxide;

DOI:10.1039/c7md00268h

Reference yield:

→ 7-(benzyloxy)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (6301-83-3)

Guidance literature:

2,4,5-Triamino-6-chlor-pyrimidin (II) 1) Iso-amylnitrit, Dioxan 2) Na-benzylat;

upstream raw materials:

2,4,5-triamino-6-benzyloxy-pyrimidine

Downstream raw materials:

2-(8-aza-O⁶-benzylguan-9-yl)ethyl-β-D-tetra-O-acetylglucoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6301-83-3 7-(benzyloxy)-7aH-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send