Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)-

Base Information

Chemical Name:Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)-
CAS No.:124444-87-7
Molecular Formula:C17H19 N3 O2
Molecular Weight:297.3517
Hs Code.:
DSSTox Substance ID:DTXSID40154394
Wikidata:Q83021609
Mol file:124444-87-7.mol

Synonyms:Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)-;124444-87-7;B-1 280;1-(4-Methoxyphenyl)-4-(3-pyridinylcarbonyl)piperazine;[4-(4-methoxyphenyl)piperazin-1-yl]-pyridin-3-ylmethanone;4-(4-methoxyphenyl)piperazinyl 3-pyridyl ketone;DTXSID40154394;AKOS003297667;CCG-329302;AE-641/00361023;3-[4-(4-methoxyphenyl)piperazin-1-ylcarbonyl]pyridine;methyl 4-[4-(3-pyridinylcarbonyl)-1-piperazinyl]phenyl ether

Suppliers and Price of Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)-

Chemical Property:

Vapor Pressure:1.35E-10mmHg at 25°C
Boiling Point:512°Cat760mmHg
Flash Point:263.4°C
Density:1.203g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:297.147726857
Heavy Atom Count:22
Complexity:361

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CN=CC=C3

Technology Process of Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)-

There total 2 articles about Piperazine, 1-(4-methoxyphenyl)-4-(3-pyridinylcarbonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 10400-19-8
3-pyridinecarbonyl chloride

: 38212-30-5
4-(4-methoxyphenyl)piperazine

: 124444-87-7
1-(4-methoxyphenyl)-4-nicotinoylpiperazine

Guidance literature:: With pyridine; In dichloromethane; for 2h; Heating;
DOI:10.1135/cccc19942343

Reference yield:

: 59-67-6
nicotinic acid

: 124444-87-7
1-(4-methoxyphenyl)-4-nicotinoylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine, SOCl₂ / CH₂Cl₂ / 1.) 0-5 deg C, 20 min, 2.) 40 deg C, 20 min

2: 84 percent / pyridine / CH₂Cl₂ / 2 h / Heating

With pyridine; thionyl chloride; In dichloromethane;
DOI:10.1135/cccc19942343

Reference yield: 98.0%

: 124444-87-7
1-(4-methoxyphenyl)-4-nicotinoylpiperazine

: 160539-82-2
1-(4-methoxyphenyl)-4-(3-pyridylmethyl)piperazine

Guidance literature:: With sodium tetrahydroborate; boron trifluoride diethyl etherate; In tetrahydrofuran; 1.) room temperature, 2 h, 2.) reflux, 4 h;
DOI:10.1135/cccc19942343