Adenylyl-(2'-5')-adenosine

Base Information

• Chemical Name: Adenylyl-(2'-5')-adenosine
• CAS No.: 2273-76-9
• Molecular Formula: C20H25 N10 O10 P
• Molecular Weight: 596.453
• European Community (EC) Number: 218-884-3
• DSSTox Substance ID: DTXSID901311243
• Nikkaji Number: J213.156K
• Wikidata: Q27145551
• Mol file: 2273-76-9.mol

Synonyms:A2'-5'A;A2'P5'A;adenylyl-(2'-5')-adenosine;ammonium adenylyl-2',5'-adenosine

Chemical Property of Adenylyl-(2'-5')-adenosine

Chemical Property:

• Boiling Point: 1081.3°Cat760mmHg
• Flash Point: 607.8°C
• Density: 2.32g/cm³
• XLogP3: -4.4
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 8
• Exact Mass: 596.14927403
• Heavy Atom Count: 41
• Complexity: 980

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OC4C(C(OC4N5C=NC6=C(N=CN=C65)N)CO)O)O)O)N
• Isomeric SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O[C@@H]4[C@@H]([C@H](O[C@H]4N5C=NC6=C(N=CN=C65)N)CO)O)O)O)N

Technology Process of Adenylyl-(2'-5')-adenosine

There total 20 articles about Adenylyl-(2'-5')-adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ATP (56-65-5,896506-78-8) → adenylyl(2'-5')adenylyl(2'-5')adenosine (70062-83-8) + adenylyl-(2'->5')-adenylyl-(2'->5')-adenylyl-(2'->5')-adenosine (73853-00-6) + adenylyl(3'-5')phosphoadenine (2273-76-9) + adenosine (58-61-7)

Guidance literature:

ATP; With potassium chloride; magnesium chloride; at 37 ℃; for 1h; pH=8; aq. buffer; Enzymatic reaction;

With shrimp alkaline phosphatase; magnesium chloride; at 37 ℃; for 1h; pH=8; aq. buffer; Enzymatic reaction;

DOI:10.3390/md8020235

Reference yield:

ATP (56-65-5,896506-78-8) → adenylyl(2'-5')adenylyl(2'-5')adenosine (70062-83-8) + adenylyl-(2'->5')-adenylyl-(2'->5')-adenylyl-(2'->5')-adenosine (73853-00-6) + A2'p5'A2'p5'A2'p5'A2'p5'A (73853-01-7) + adenylyl(3'-5')phosphoadenine (2273-76-9) + adenosine (58-61-7)

Guidance literature:

ATP; With potassium chloride; magnesium chloride; at 37 ℃; for 17h; pH=8; aq. buffer; Enzymatic reaction;

With shrimp alkaline phosphatase; magnesium chloride; at 37 ℃; for 1h; pH=8; aq. buffer; Enzymatic reaction;

DOI:10.3390/md8020235

Reference yield:

3'-O-(acetyloxymethyl)adenosin-2'-yl adenosin-5'-yl 3-(acetyloxy)-2,2-bis(ethoxycarbonyl)propyl phosphate (1259402-79-3) → C21H30N5O13P (1281797-14-5) + C21H30N5O13P (1281797-12-3) + Inosine (58-63-9) + adenylyl(3'-5')phosphoadenine (2273-76-9) + adenosine (58-61-7)

Guidance literature:

With hog liver carboxyesterase; water; sodium chloride; at 37 ℃; pH=7.5; HEPES buffer; Enzymatic reaction;

DOI:10.1002/cbdv.201000288

upstream raw materials:

p5'A₂'p5'A₃'p5'A₂'p5'A

2',3'-di-O-acetyladenosine

O^5'-acetyl-O^2'_,O3'-hydroxyphosphoryl-adenosine

adenosine monophosphate

Downstream raw materials:

5'-adenosine monophosphate

adenosine

adenosine monophosphate

adenosine 2'-monophosphate