2,4-Bis(trifluoromethyl)thiophene

Base Information

• Chemical Name: 2,4-Bis(trifluoromethyl)thiophene
• CAS No.: 87721-34-4
• Molecular Formula: C6H2F6S
• DSSTox Substance ID: DTXSID80516058
• Wikidata: Q82377282
• Mol file: 87721-34-4.mol

Synonyms:2,4-Bis(trifluoromethyl)thiophene;87721-34-4;SCHEMBL16467657;DTXSID80516058;RCRRYAXQJRZEKK-UHFFFAOYSA-N

Chemical Property of 2,4-Bis(trifluoromethyl)thiophene

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 0
• Exact Mass: 219.97814021
• Heavy Atom Count: 13
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(SC=C1C(F)(F)F)C(F)(F)F

Technology Process of 2,4-Bis(trifluoromethyl)thiophene

There total 6 articles about 2,4-Bis(trifluoromethyl)thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3,3-trifluoroprop-1-yne (661-54-1) + hexafluoro-2-butyne (692-50-2) → tetrakis(trifluoromethyl)thiophene (651-93-4) + 2,4-bis(trifluoromethyl)thiophene (87721-34-4) + hexakis(trifluoromethyl)dewar benzene (87721-35-5) + 2,3,4-tris(trifluoromethyl)thiophene (87721-36-6)

Guidance literature:

With carbon oxide sulfide; at 150 ℃; for 1h; Yield given. Further byproducts given. Yields of byproduct given; Irradiation;

Reference yield:

3,3,3-trifluoroprop-1-yne (661-54-1) → 1,3,5-tris(trifluoromethyl)benzene (729-81-7) + 2,5-bis(trifluoromethyl)thiophene (87721-33-3) + 2,4-bis(trifluoromethyl)thiophene (87721-34-4) + 3,3,3-trifluoromethylthioketene (87721-32-2)

Guidance literature:

With carbon oxide sulfide; at 150 ℃; Yield given. Further byproducts given. Yields of byproduct given; Irradiation;

Reference yield:

3,3,3-trifluoroprop-1-yne (661-54-1) → 2,5-bis(trifluoromethyl)thiophene (87721-33-3) + 2-(trifluoromethyl)thiophene (86093-76-7) + 2,4-bis(trifluoromethyl)thiophene (87721-34-4) + 3,3,3-trifluoromethylthioketene (87721-32-2)

Guidance literature:

With carbon oxide sulfide; at 150 ℃; Yield given. Further byproducts given. Yields of byproduct given; Irradiation;

upstream raw materials:

3,3,3-trifluoroprop-1-yne

2,3-bis(trifluoromethyl)thiophene

hexafluoro-2-butyne