Efloxate

Base Information

Chemical Name:Efloxate
CAS No.:119-41-5
Molecular Formula:C19H16 O5
Molecular Weight:324.333
Hs Code.:2918990090
European Community (EC) Number:204-321-9
NSC Number:758891
UNII:CZU6V3902K
DSSTox Substance ID:DTXSID3048736
Nikkaji Number:J2.479A
Wikipedia:Efloxate
Wikidata:Q962269
NCI Thesaurus Code:C74416
Metabolomics Workbench ID:154151
ChEMBL ID:CHEMBL1349073
Mol file:119-41-5.mol

Synonyms:efloxate;Recordil

Suppliers and Price of Efloxate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Efloxate 98+%
50mg
$ 55.00

American Custom Chemicals Corporation
EFLOXATE 95.00%
5G
$ 1443.17

Total 17 raw suppliers

Chemical Property of Efloxate

Chemical Property:

Vapor Pressure:1.28E-09mmHg at 25°C
Melting Point:123-124°
Refractive Index:1.6120 (estimate)
Boiling Point:486.5°C at 760 mmHg
Flash Point:269.1°C
PSA：65.74000
Density:1.265g/cm³
LogP:3.40190
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:324.09977361
Heavy Atom Count:24
Complexity:492

Purity/Quality:

97% ^*data from raw suppliers

Efloxate 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)COC1=CC2=C(C=C1)C(=O)C=C(O2)C3=CC=CC=C3

Technology Process of Efloxate

There total 14 articles about Efloxate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

: 6665-86-7,66585-10-2
7-hydroxyflavone

: 105-39-5
chloroacetic acid ethyl ester

: 119-41-5
7-ethoxycarbonylmethoxyflavone

Guidance literature:: With potassium carbonate; sodium iodide; In acetone; for 48h; Reflux;
DOI:10.1007/s00044-015-1317-9

Reference yield: 61.0%

: 7436-90-0
2,2-dibromostyrene

: 96089-43-9
2-hydroxy-4-<(carboxymethyl)oxy>benzaldehyde ethyl ester

: 119-41-5
7-ethoxycarbonylmethoxyflavone

Guidance literature:: With chlorocarbonylbis(triphenylphosphine)rhodium(I); potassium carbonate; In N,N-dimethyl acetamide; at 90 ℃; for 5h; Schlenk technique; Inert atmosphere;
DOI:10.1039/c9ob02670c

Reference yield: 44.0%

: 6665-86-7,66585-10-2
7-hydroxyflavone

: 105-36-2
ethyl bromoacetate

: 119-41-5
7-ethoxycarbonylmethoxyflavone

Guidance literature:: 7-hydroxyflavone; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

ethyl bromoacetate; In N,N-dimethyl-formamide; at 70 ℃; for 2h;
DOI:10.1016/j.bmcl.2018.07.006