Pyridine, 2-[3-[4-(dodecyloxy)phenyl]-1H-pyrazol-1-yl]-

Base Information

• Chemical Name: Pyridine, 2-[3-[4-(dodecyloxy)phenyl]-1H-pyrazol-1-yl]-
• CAS No.: 879294-62-9
• Molecular Formula: C₂₆H₃₅N₃O
• Molecular Weight: 405.583
• Mol file: 879294-62-9.mol

Synonyms:

Chemical Property of Pyridine, 2-[3-[4-(dodecyloxy)phenyl]-1H-pyrazol-1-yl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pyridine, 2-[3-[4-(dodecyloxy)phenyl]-1H-pyrazol-1-yl]-

There total 2 articles about Pyridine, 2-[3-[4-(dodecyloxy)phenyl]-1H-pyrazol-1-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-dodecyloxy-phenyl)-ethanone (2175-80-6) → 2-[3-(4-dodecyloxyphenyl)pyrazol-1-yl]pyridine (879294-62-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydride / toluene / 20 °C

2: hydrochloric acid / ethanol; H₂O / 3 h / Heating

With hydrogenchloride; sodium hydride; In ethanol; water; toluene;

DOI:10.1016/j.jorganchem.2005.09.053

Reference yield:

pyrid-2-ylhydrazine (4930-98-7) + Sodium; (Z)-3-(4-dodecyloxy-phenyl)-3-oxo-propen-1-olate → 2-[3-(4-dodecyloxyphenyl)pyrazol-1-yl]pyridine (879294-62-9)

Guidance literature:

With hydrogenchloride; In ethanol; water; for 3h; Heating;

DOI:10.1016/j.jorganchem.2005.09.053

Reference yield: 44.0%

2-[3-(4-dodecyloxyphenyl)pyrazol-1-yl]pyridine (879294-62-9) + bis(benzonitrile)palladium(II) dichloride (15617-18-2,39958-10-6,14220-64-5) + dichloromethane (75-09-2) → cis-[PdCl2(2-[3-(4-dodecyloxyphenyl)pyrazol-1-yl]pyridine)]*3/4(dichloromethane)

Guidance literature:

In chloroform; to a soln. of a ligand (0.130 mmol) in chloroform was added Pd-contg. compd. (0.130 mmol); the mixt. was refluxed for 3 h and then left stirringovernight at room temp.; the solvent was removed and the solid recrystd. in CH2Cl2/hexane; the solid was filtered off, washed with hexane and dried in vac.; elem. anal.;

DOI:10.1016/j.jorganchem.2005.09.053

upstream raw materials:

pyrid-2-ylhydrazine

1-(4-dodecyloxy-phenyl)-ethanone

Downstream raw materials:

c-[Pd(η3-C3H5)(2-[3-(4-dodecyloxyphenyl)pyrazol-1-yl]pyridine)]BF4