1,2-Pyrrolidinedicarboxylic acid, 2-[(1R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-ethenylbutyl]-5-[(phenyl methoxy)methyl]-, 1-(1,1-dimethylethyl) ester, (2S,5S)-

Base Information

Chemical Name:1,2-Pyrrolidinedicarboxylic acid, 2-[(1R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-ethenylbutyl]-5-[(phenyl methoxy)methyl]-, 1-(1,1-dimethylethyl) ester, (2S,5S)-
CAS No.:879572-68-6
Molecular Formula:C40H53NO6Si
Molecular Weight:671.949
Hs Code.:

1,2-Pyrrolidinedicarboxylic acid,
2-[(1R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-ethenylbutyl]-5-[(phenyl
methoxy)methyl]-, 1-(1,1-dimethylethyl) ester, (2S,5S)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2-Pyrrolidinedicarboxylic acid, 2-[(1R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-ethenylbutyl]-5-[(phenyl methoxy)methyl]-, 1-(1,1-dimethylethyl) ester, (2S,5S)-

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Technology Process of 1,2-Pyrrolidinedicarboxylic acid, 2-[(1R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-ethenylbutyl]-5-[(phenyl methoxy)methyl]-, 1-(1,1-dimethylethyl) ester, (2S,5S)-

There total 1 articles about 1,2-Pyrrolidinedicarboxylic acid, 2-[(1R)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-ethenylbutyl]-5-[(phenyl methoxy)methyl]-, 1-(1,1-dimethylethyl) ester, (2S,5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: (2S,5S)-(E)-1-tert-butyl 2-[6-(tert-butyldiphenylsilyloxy)hex-2-enyl] 5-(benzyloxymethyl)pyrrolidine-1,2-dicarboxylate

: 879572-68-6
(2S,5S)-5-(benzyloxymethyl)-1-(tert-butoxycarbonyl)-2-[(R)-6-(tert-butyldiphenylsilyloxy)hex-1-en-3-yl]pyrrolidine-2-carboxylic acid

: C₄₀H₅₃NO₆Si

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; for 24h; Reagent/catalyst; Solvent; diastereoselective reaction; Inert atmosphere;
DOI:10.1002/chem.201404316