2-PropionaMidopropanoic acid

Base Information

• Chemical Name: 2-PropionaMidopropanoic acid
• CAS No.: 56440-46-1
• Molecular Formula: C6H11NO3
• Molecular Weight: 145.1564
• Hs Code.: 2924199090
• Mol file: 56440-46-1.mol

Synonyms:N-PROPIONYLALANINE;N-propionyl-L-alanine;2-propanamidopropanoic acid;2-(propionylamino)propanoic acid;N-propanoylalanine;

Chemical Property of 2-PropionaMidopropanoic acid

Chemical Property:

• Vapor Pressure: 1.97E-06mmHg at 25°C
• Boiling Point: 368.2°Cat760mmHg
• Flash Point: 176.5°C
• PSA: 66.40000
• Density: 1.129g/cm³
• LogP: 0.37660

Purity/Quality:

98%min ^*data from raw suppliers

N-Propionylalanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-PropionaMidopropanoic acid

There total 2 articles about 2-PropionaMidopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-alanin (56-41-7,25191-17-7,18875-37-1) + propionyl chloride (79-03-8) → N-propionyl-L-alanine (56440-46-1)

Guidance literature:

L-alanin; propionyl chloride; With sodium hydroxide; In water; at 0 - 20 ℃;

With hydrogenchloride; In water; at 0 ℃;

DOI:10.1002/mrc.2374

Reference yield:

C10H19NO3 → N-propionyl-L-alanine (56440-46-1)

Guidance literature:

With trifluoroacetic acid;

DOI:10.1016/j.ejmech.2008.06.022

Reference yield: 51.0%

1-(4-cyanophenyl)-3-methyltriazene (51029-20-0) + N-propionyl-L-alanine (56440-46-1) → 1-(4-cyanophenyl)-3-methyl-3-(2-(propanoylamino)propanoyl)triazene (1147743-41-6)

Guidance literature:

N-propionyl-L-alanine; With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 0.5h;

1-(4-cyanophenyl)-3-methyltriazene; With triethylamine; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1016/j.ejmech.2008.06.022

upstream raw materials:

L-alanin

propionyl chloride

Downstream raw materials:

1-(4-cyanophenyl)-3-methyl-3-(2-(propanoylamino)propanoyl)triazene

Refernces

• 1、 Gomez, Edison Diaz,Duddeck, Helmut. "A new method proposed for the determination of absolute configurations of α-amino acids". experimental part. p. 222 - 227. Retrieved 2010/02/28.