2-[(4-Chlorophenyl)hydrazinylidene]propanoic acid

Base Information

• Chemical Name: 2-[(4-Chlorophenyl)hydrazinylidene]propanoic acid
• CAS No.: 5436-18-0
• Molecular Formula: C9H9ClN2O2
• Molecular Weight: 212.636
• NSC Number: 21417
• Mol file: 5436-18-0.mol

Synonyms:2-[(4-chlorophenyl)hydrazinylidene]propanoic acid;5436-18-0;NSC21417;NSC-21417

Chemical Property of 2-[(4-Chlorophenyl)hydrazinylidene]propanoic acid

Chemical Property:

• Vapor Pressure: 1.1E-05mmHg at 25°C
• Boiling Point: 356°Cat760mmHg
• Flash Point: 169.1°C
• Density: 1.31g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 212.0352552
• Heavy Atom Count: 14
• Complexity: 235

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NNC1=CC=C(C=C1)Cl)C(=O)O
• Isomeric SMILES: C/C(=N\NC1=CC=C(C=C1)Cl)/C(=O)O

Technology Process of 2-[(4-Chlorophenyl)hydrazinylidene]propanoic acid

There total 1 articles about 2-[(4-Chlorophenyl)hydrazinylidene]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-oxo-propionic acid (127-17-3) → 2-(4-chloro-phenylhydrazono)-propionic acid (5436-18-0)

Guidance literature:

With water;

Reference yield: 76.0%

2-(4-chlorophenylhydrazono)propionic acid (5436-18-0) + 4-methoxy-benzylamine (2393-23-9) → N-(4-methoxybenzyl)-2-(4-chlorophenylhydrazono)propionic acid amide

Guidance literature:

2-(4-chlorophenylhydrazono)propionic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

4-methoxy-benzylamine; In tetrahydrofuran; for 15h;

Reference yield:

ethanol (64-17-5) + 2-(4-chloro-phenylhydrazono)-propionic acid (5436-18-0) → 2-[(4-chlorophenyl)-hydrazono]-propionic acid ethyl ester (5296-86-6)

Guidance literature:

With sulfuric acid;

upstream raw materials:

2-oxo-propionic acid

Downstream raw materials:

2-[(4-chlorophenyl)-hydrazono]-propionic acid ethyl ester