2-Chloro-1-methyl-1H-imidazole

Base Information

Chemical Name:2-Chloro-1-methyl-1H-imidazole
CAS No.:253453-91-7
Molecular Formula:C4H5 Cl N2
Molecular Weight:116.55
Hs Code.:2933290090
European Community (EC) Number:681-783-1
DSSTox Substance ID:DTXSID50378382
Nikkaji Number:J1.193.608C
Wikidata:Q72454068
Mol file:253453-91-7.mol

Synonyms:2-Chloro-1-methyl-1H-imidazole;253453-91-7;2-chloro-1-methylimidazole;MFCD02179531;1H-IMIDAZOLE, 2-CHLORO-1-METHYL-;SCHEMBL1701532;1-Methyl-2-chloro-1H-imidazole;DTXSID50378382;VSCQFRRKWFQPOA-UHFFFAOYSA-N;AMY11600;BBL102976;STL556785;AKOS005255505;AB11324;PS-3321;AC-28871;SY019835;2-chloro-1-methyl-1H-imidazole, AldrichCPR;A5119;CS-0101166;FT-0644131;EN300-82854;Y10383;Q-200535;W-206949

Suppliers and Price of 2-Chloro-1-methyl-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-1-methyl-1H-imidazole
100mg
$ 65.00

TRC
2-Chloro-1-methyl-1H-imidazole
500mg
$ 220.00

SynQuest Laboratories
2-Chloro-1-methyl-1H-imidazole 95.0%
1 g
$ 280.00

Matrix Scientific
2-Chloro-1-methyl-1H-imidazole 97%
5g
$ 2016.00

Matrix Scientific
2-Chloro-1-methyl-1H-imidazole 97%
1g
$ 572.00

Matrix Scientific
2-Chloro-1-methyl-1H-imidazole 97%
500mg
$ 341.00

Frontier Specialty Chemicals
2-Chloro-1-methyl-1H-imidazole 98%
1g
$ 120.00

Chemenu
2-chloro-1-methyl-1H-imidazole 95+%
10g
$ 611.00

Chemenu
2-chloro-1-methyl-1H-imidazole 95+%
1g
$ 86.00

Chemenu
2-chloro-1-methyl-1H-imidazole 95+%
5g
$ 323.00

Total 72 raw suppliers

Chemical Property of 2-Chloro-1-methyl-1H-imidazole

Chemical Property:

Vapor Pressure:0.153mmHg at 25°C
Melting Point:-10℃
Boiling Point:214.8°Cat760mmHg
PKA:4.00±0.25(Predicted)
Flash Point:83.7°C
PSA：17.82000
Density:1.26g/cm³
LogP:1.07350
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:0.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:116.0141259
Heavy Atom Count:7
Complexity:66.7

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-1-methyl-1H-imidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=CN=C1Cl
Uses 2-Chloro-1-methylimidazole is used in pharmaceuticals, drug candidates, ligands for transition metal catalysts and other molecular functional materials.

Technology Process of 2-Chloro-1-methyl-1H-imidazole

There total 3 articles about 2-Chloro-1-methyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 616-47-7
1-methyl-1H-imidazole

: 253453-91-7
2-chloro-1-methyl-1H-imidazole

Guidance literature:: 1-methyl-1H-imidazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With hexachloroethane; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.tetlet.2015.04.094

Reference yield:

: 2-Chloro-3-(4-methoxy-benzyl)-1-methyl-3H-imidazol-1-ium; chloride

: 253453-91-7
2-chloro-1-methyl-1H-imidazole

Guidance literature:: With ammonium cerium(IV) nitrate; In acetonitrile; at 70 ℃; for 1h;

Reference yield:

: Toluene-4-sulfonate3-(4-methoxy-benzyl)-1-methyl-3H-imidazol-1-ium;

: 253453-91-7
2-chloro-1-methyl-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: NaH, C₂Cl₆ / dimethylformamide / 24 h / 20 °C

2: CAN / acetonitrile / 1 h / 70 °C

With ammonium cerium(IV) nitrate; hexachloroethane; sodium hydride; In N,N-dimethyl-formamide; acetonitrile;