4-Isopropylbenzophenone

Base Information

• Chemical Name: 4-Isopropylbenzophenone
• CAS No.: 18864-76-1
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Hs Code.: 2914399090
• Mol file: 18864-76-1.mol

Synonyms:4-Isopropylbenzophenone;Benzophenone,4-isopropyl;Methanone,[4-(1-methylethyl)phenyl]phenyl;

Chemical Property of 4-Isopropylbenzophenone

Chemical Property:

• Vapor Pressure: 0.000113mmHg at 25°C
• Boiling Point: 336.3°Cat760mmHg
• Flash Point: 142.8°C
• PSA: 17.07000
• Density: 1.03g/cm³
• LogP: 4.04100

Purity/Quality:

99% ^*data from raw suppliers

(4-Isopropylphenyl)-phenyl-methanone 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Isopropylbenzophenone

There total 26 articles about 4-Isopropylbenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(+/-)-(4-isopropylphenyl)phenylmethanol (22543-72-2) → 4-isopropylbenzophenone (18864-76-1)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.1c00889

Reference yield: 80.0%

Isopropylbenzene (98-82-8) + benzoic acid anhydride (93-97-0) → 4-isopropylbenzophenone (18864-76-1) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With Cl^(1-)*C₅H₁₄NO⁽¹⁺⁾*3ZnCl₂; at 140 ℃; for 0.333333h; Microwave irradiation; Green chemistry;

DOI:10.1039/c6ra03551e

Reference yield: 74.0%

p-isopropylbenzoic acid (536-66-3) + phenylboronic acid (98-80-6) → 4-isopropylbenzophenone (18864-76-1)

Guidance literature:

p-isopropylbenzoic acid; With potassium phosphate; In 1,4-dioxane; at 20 ℃; for 0.0833333h; Inert atmosphere;

With 2-chloro-1,3-dimethylimidazolinium chloride; In 1,4-dioxane; at 20 ℃; for 2h; Inert atmosphere;

phenylboronic acid; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 90 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1016/j.tetlet.2013.02.038

upstream raw materials:

Isopropylbenzene

benzoyl chloride

Phenetole

p-isopropylbenzoyl chloride

Downstream raw materials:

2-(4-bromo-phenyl)-3-(4-isopropyl-phenyl)-3-phenyl-acrylonitrile

(4-isopropylphenyl)diphenylmethanol

1-isopropyl-4-(1-phenylvinyl)benzene

phenyl (4-isopropylphenyl) methane