1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE

Base Information

Chemical Name:1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE
CAS No.:89488-02-8
Molecular Formula:C6H5N3O2
Molecular Weight:151.125
Hs Code.:
Mol file:89488-02-8.mol

Synonyms:1H-Pyrrole-2-carbonitrile,1-methyl-4-nitro;1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE;

Suppliers and Price of 1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE 95.00%
5MG
$ 502.27

Alichem
1-Methyl-4-nitro-1h-pyrrole-2-carbonitrile
1g
$ 907.50

Total 4 raw suppliers

Chemical Property of 1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE

Chemical Property:

PSA：74.54000
LogP:1.32818

Purity/Quality:

98%min ^*data from raw suppliers

1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE

There total 12 articles about 1-METHYL-4-NITRO-1H-PYRROLE-2-CARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 59027-78-0
4-nitro-1H-pyrrole-2-carbonitrile

: 74-88-4
methyl iodide

: 89488-02-8
1-methyl-4-nitro-pyrrolecarbonitrile

Guidance literature:: 4-nitro-1H-pyrrole-2-carbonitrile; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/acs.jmedchem.8b01147

Reference yield: 73.7%

: 34884-10-1
1-methyl-1H-pyrrole-2-carbonitrile

: 89488-02-8
1-methyl-4-nitro-pyrrolecarbonitrile

Guidance literature:: With sodium hydroxide; nitric acid; In ice-water; acetic acid;

Reference yield:

: 5930-93-8
4-nitropyrrole-2-carboxylic acid

: 89488-02-8
1-methyl-4-nitro-pyrrolecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonia; 1,1'-carbonyldiimidazole / tetrahydrofuran / 20 °C

1.2: 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide / 0 °C

With ammonia; sodium hydride; 1,1'-carbonyldiimidazole; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2017.11.037