7-NITRO-2(1H)-QUINOXALINONE

Base Information

• Chemical Name: 7-NITRO-2(1H)-QUINOXALINONE
• CAS No.: 89898-96-4
• Molecular Formula: C8H5N3O3
• Molecular Weight: 191.146
• Hs Code.: 2933990090
• Mol file: 89898-96-4.mol

Synonyms:7-nitro-1H-quinoxalin-2-one;

Chemical Property of 7-NITRO-2(1H)-QUINOXALINONE

Chemical Property:

• Melting Point: 275-276 °C
• PKA: 7.85±0.70(Predicted)
• PSA: 91.57000
• Density: 1?+-.0.1 g/cm3(Predicted)
• LogP: 1.35450
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

7-Nitro-1,2-dihydroquinoxalin-2-one >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-NITRO-2(1H)-QUINOXALINONE

There total 1 articles about 7-NITRO-2(1H)-QUINOXALINONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

1,1-Diphenylethylene (530-48-3) + quinoxalin-2(1)-one (1196-57-2) → 7-nitroquinoxaline-2(1H)-one (89898-96-4) + 1,1'-(2-nitroethene-1,1-diyl)dibenzene (5670-69-9)

Guidance literature:

With tert.-butylnitrite; In acetonitrile; at 60 ℃; for 6h;

DOI:10.1039/d1ob02015c

Reference yield: 96.0%

2-Hydroxy-7-nitroquinoxaline (89898-96-4) → 2-Chloro-7-nitroquinoxaline (55686-94-7)

Guidance literature:

With trichlorophosphate; for 3h; Reflux;

DOI:10.21577/0103-5053.20170018

Reference yield: 93.0%

7-nitroquinoxaline-2(1H)-one (89898-96-4) + 5,7-dihydroxy-4-phenyl-2H-1-benzopyran-2-one (7758-73-8) → 3-(5,7-dihydroxy-4-phenyl-2-oxo-2H-chromen-8-yl)-7-nitro-3,4-dihydroquinoxalin-2(1H)-one

Guidance literature:

With boron trifluoride diethyl etherate; In methanol; for 4h; regioselective reaction; Reflux;

DOI:10.1055/s-0037-1609482

upstream raw materials:

1,1-Diphenylethylene

quinoxalin-2⁽¹⁾-one

Downstream raw materials:

7-aminoquinoxalin-2(1H)-one

2-Chloro-7-nitroquinoxaline

6-amino-3-chloroquinoxaline

(E)-3-(3-(6-nitroquinoxalin-3-ylamino)phenyl)acrylic acid

Refernces