7758-73-8

Basic information

• Product Name: 5 7-DIHYDROXY-4-PHENYLCOUMARIN
• Synonyms: 5,7-Dihydroxy-4-phenyl-2H-1-benzopyran-2-one;5,7-Dihydroxy-4-phenyl-2H-chromen-2-one;Serratin;2H-1-Benzopyran-2-one, 5,7-dihydroxy-4-phenyl-;5,7-dihydroxy-4-phenyl-2-chromenone;5,7-Dihydroxy-4-phenyl-chromen-2-one;5,7-dihydroxy-4-phenylchromen-2-one
• CAS NO: 7758-73-8
• Molecular Formula: C₁₅H₁₀O₄
• Molecular Weight: 254.24
• Product Categories: Coumarin;Building Blocks;Coumarins;Heterocyclic Building Blocks;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 7758-73-8.mol
• Article Data: 59

Chemical Properties

• Melting Point: 227-233 °C(lit.)
• Boiling Point: 535.5 °C at 760 mmHg
• Flash Point: 210.5 °C
• Appearance: /
• Density: 1.443
• Vapor Pressure: 4.42E-12mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 5 7-DIHYDROXY-4-PHENYLCOUMARIN(CAS DataBase Reference)
• NIST Chemistry Reference: 5 7-DIHYDROXY-4-PHENYLCOUMARIN(7758-73-8)
• EPA Substance Registry System: 5 7-DIHYDROXY-4-PHENYLCOUMARIN(7758-73-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 7758-73-8(Hazardous Substances Data)

Usage

General Description

5 7-Dihydroxy-4-phenylcoumarin is a chemical compound with potential pharmaceutical properties. It is a coumarin derivative that has been studied for its antioxidant and anti-inflammatory properties, as well as its potential in the treatment of cardiovascular diseases. The compound has also shown potential as a natural sunscreen agent, with studies suggesting its ability to protect the skin from harmful UV radiation. Additionally, 5 7-Dihydroxy-4-phenylcoumarin has been investigated for its potential in cancer therapy, with research indicating its ability to induce apoptosis in cancer cells. Overall, this compound shows promise for a wide range of medicinal applications and continues to be the subject of ongoing research.

InChI:InChI=1/C15H10O4/c16-10-6-12(17)15-11(9-4-2-1-3-5-9)8-14(18)19-13(15)7-10/h1-8,16-17H

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 533-73-3 1,2,4-Trihydroxybenzene 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 6864-62-6 phenyl acetoacetate 
• 103-26-4 methyl cinnamate 
• 621-82-9 Cinnamic acid 
• 100-52-7 benzaldehyde 
• 21770-48-9 methyl 2,3-dibromo-3-phenylpropanoate 
• 911217-72-6 C₁₇H₁₁F₁₃O₃ 
• 98-86-2 acetophenone 
• 141-97-9 ethyl acetoacetate 
• 637-44-5 phenylpropyolic acid 
• 2732-18-5 5,7-dihydroxy-2H-chromen-2-one 
• 587-85-9 diphenylmercury(II) 

Downstream Products

• 36701-49-2 6-allyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one 
• 98192-57-5 5,7-dihydroxy-6-(3-methylbutanoyl)-4-phenyl-2H-chromen-2-one 
• 98192-64-4 5,7-dihydroxy-8-(2-methyl-1-oxobutyl)-4-phenyl-2H-[1]benzopyran-2-one 
• 213834-81-2 6-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one 
• 213834-75-4 8-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one 
• 57057-52-0 8-acetyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one 
• 57391-54-5 1,1'-(5,7-dihydroxy-2-oxo-4-phenyl-2H-chromene-6,8-diyl)diethanone 
• 307547-68-8 5,7-dibenzyloxy-4-phenyl-2H-chromen-2-one 

Relevant articles and documents

TWO NEW NEOFLAVONOIDS AND C-GLYCOSYLFLAVONES FROM PASSIFLORA SERRATODIGITATA

The aerial parts of Passiflora serratodigitata yielded 5,7-dihydroxy-4-phenylcoumarin, its 7-β-glucoside and the known C-glycosylflavones 2"-xylosylvitexin, 2"-xylosylisovitexin, vitexin, isovitexin, avicenin, and orientin.The known flavone chrysin was also isolated.This is the first report of neoflavonoids in the family Passifloraceae.Key Word Index - Passiflora serratodigitata; Passifloraceae; 5,7-dihydroxy-4-phenylcoumarin (serratin); serratin 7-β-glucoside; C-glycosylflavones.

Synthesis of novel coumarin containing conjugated fluorescent polymers by Suzuki cross-coupling reactions and their chemosensing studies for iron and mercury ions

Conjugated fluorescent polymers are very useful materials for chemical and biochemical sensors. Herein we report the synthesis of four novel conjugated coumarin-containing fluorescent co-polymers (P1–P4) by palladium catalyzed Suzuki-Miyaura cross-couplin

Compounds for preventing or treating lipid metabolism-related diseases

The present invention relates to the field of biomedicines, and in particular to a structure capable of binding LC3 and a structure capable of binding a lipid droplet linked together by a covalent linkage, thereby forming a 'LC3 binding moiety - lipid dro

Investigation of HMG-CoA reductase inhibitory and antioxidant effects of various hydroxycoumarin derivatives

Cardiovascular diseases are one of the primary causes of deaths worldwide, and the development of atherosclerosis is closely related to hypercholesterolemia. As the reduction of the low-density lipoprotein cholesterol level is critical for treating these