N-[4-(hydroxymethyl)phenyl]benzenesulfonamide

Base Information

Chemical Name:N-[4-(hydroxymethyl)phenyl]benzenesulfonamide
CAS No.:90312-03-1
Molecular Formula:C13H13NO3S
Molecular Weight:263.317
Hs Code.:
DSSTox Substance ID:DTXSID60392418

Synonyms:N-[4-(hydroxymethyl)phenyl]benzenesulfonamide;SCHEMBL2822371;DTXSID60392418;AKOS014121748;90312-03-1

Suppliers and Price of N-[4-(hydroxymethyl)phenyl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-[4-(hydroxymethyl)phenyl]benzenesulfonamide

Chemical Property:

Vapor Pressure:3.87E-09mmHg at 25°C
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:263.06161445
Heavy Atom Count:18
Complexity:336

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)CO

Technology Process of N-[4-(hydroxymethyl)phenyl]benzenesulfonamide

There total 6 articles about N-[4-(hydroxymethyl)phenyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 623-04-1
4-aminobenzenemethanol

: 98-09-9
benzenesulfonyl chloride

: 90312-03-1
N-(4-hydroxymethylphenyl)benzenesulfonamide

Guidance literature:: With pyridine; at 60 ℃;
DOI:10.1016/j.bmc.2006.12.026

Reference yield: 46.0%

: 89113-18-8
ethyl 4-benzoate

: 90312-03-1
N-(4-hydroxymethylphenyl)benzenesulfonamide

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 5 - 45 ℃; for 4h;
DOI:10.1016/S0968-0896(97)10009-8

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 90312-03-1
N-(4-hydroxymethylphenyl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 0 °C

2: DIBAL-H / tetrahydrofuran / -40 - -30 °C

With pyridine; diisobutylaluminium hydride; In tetrahydrofuran;
DOI:10.1021/jo00106a029