2-[2-(Tetrahydrofuran-2-yl)ethyl]-1,6-dioxaspiro[4.4]nonane

Base Information

• Chemical Name: 2-[2-(Tetrahydrofuran-2-yl)ethyl]-1,6-dioxaspiro[4.4]nonane
• CAS No.: 63917-47-5
• Molecular Formula: C13H22 O3
• Molecular Weight: 226.316
• Hs Code.: 2932999099
• Mol file: 63917-47-5.mol

Synonyms:1,6-Dioxaspiro[4.4]nonane,2-(2-tetrahydro-2-furylethyl)- (6CI)

Chemical Property of 2-[2-(Tetrahydrofuran-2-yl)ethyl]-1,6-dioxaspiro[4.4]nonane

Chemical Property:

• Vapor Pressure: 0.000258mmHg at 25°C
• Boiling Point: 333.8°Cat760mmHg
• Flash Point: 112°C
• PSA: 27.69000
• Density: 1.09g/cm³
• LogP: 2.63130

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[2-(Tetrahydrofuran-2-yl)ethyl]-1,6-dioxaspiro[4.4]nonane

There total 7 articles about 2-[2-(Tetrahydrofuran-2-yl)ethyl]-1,6-dioxaspiro[4.4]nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.6%

1,5-bis-(2-furanyl)-1,4-pentandien-3-one (886-77-1,144850-49-7,26375-43-9) → 2-(2-tetrahydrofurylethyl)-1,6-dioxaspiro[4.4]nonane (63917-47-5) + 1,5-di(tetrahydrofuran-2-yl)pentan-3-one (21133-22-2) + 1,5-di(furan-2-yl)pentan-3-one (6075-11-2) + 1-(2-tetrahydrofuryl)-5-(2-furyl)-3-pentanol (1221547-01-8) + 1(α-furyl)-5-(α-tetrahydrofuryl)pentan-3-one (75937-84-7)

Guidance literature:

With palladium on silica gel; hydrogen; In neat (no solvent); at 70 ℃; for 5h; under 37503.8 Torr; Autoclave;

DOI:10.1002/cssc.201701200

Reference yield: 28.4%

1,5-bis-(2-furanyl)-1,4-pentandien-3-one (886-77-1,144850-49-7,26375-43-9) → 1,5-di(2-tetrahydrofuryl)-3-pentanol (6265-26-5) + 2-(2-tetrahydrofurylethyl)-1,6-dioxaspiro[4.4]nonane (63917-47-5) + 1,5-di(tetrahydrofuran-2-yl)pentan-3-one (21133-22-2) + 1,5-di(furan-2-yl)pentan-3-one (6075-11-2) + 1-(2-tetrahydrofuryl)-5-(2-furyl)-3-pentanol (1221547-01-8) + 1(α-furyl)-5-(α-tetrahydrofuryl)pentan-3-one (75937-84-7)

Guidance literature:

With 5% Pd/zirconia; hydrogen; In neat (no solvent); at 70 ℃; for 5h; under 37503.8 Torr; Autoclave;

DOI:10.1002/cssc.201701200

Reference yield:

furfural (98-01-1) + acetone (67-64-1) → 4-tetrahydrofuran-2-yl-butan-2-ol (3208-43-3,4527-76-8) + 2-methyl-1,6-dioxa-spiro[4.4]nonane (5451-15-0) + 1,5-di(2-tetrahydrofuryl)-3-pentanol (6265-26-5) + 2-(2-tetrahydrofurylethyl)-1,6-dioxaspiro[4.4]nonane (63917-47-5)

Guidance literature:

furfural; acetone; at 140 ℃; for 5h;

With hydrogen; In isopropyl alcohol; at 140 ℃; for 10h; under 30003 Torr;

DOI:10.1016/j.catcom.2010.02.002

upstream raw materials:

(E,E)-1,5-di-(2-furyl)pent-1,4-dien-3-one

furfural

acetone

1,5-bis-(2-furanyl)-1,4-pentandien-3-one