Technology Process of Methanone, bis[3-(bromomethyl)-2-methylphenyl]-
There total 9 articles about Methanone, bis[3-(bromomethyl)-2-methylphenyl]- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sulfuric acid; hydrogen bromide;
for 12h;
Heating;
DOI:10.1021/jo00188a004
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1) Mg, 1,2-Dibromoethane / 1) in THF under refluxtemp., 2) under cooling, 45 min -> 12 h, refluxtemp.
2: 94 percent / PBr3, Py. / benzene / 2 h
3: 89 percent / methanol / 2.5 h / Heating
4: 1) Mg turnings, 1,2-dibromoethane / 1) in THF, 6-8 h, under reflux, 2) in THF, 1 h, 20 deg C -> 1h, reflux
5: 95 percent / CrO3, conc. H2SO4 / H2O; acetone
6: 74 percent / 48percent HBr, conc. H2SO4 / 12 h / Heating
With
pyridine; chromium(VI) oxide; sulfuric acid; hydrogen bromide; phosphorus tribromide; magnesium; ethylene dibromide;
In
methanol; water; acetone; benzene;
DOI:10.1021/jo00188a004
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 93 percent / NaBH4 / tetrahydrofuran / 3.5 h / 20 °C
2: 94 percent / PBr3, Py. / benzene / 2 h
3: 89 percent / methanol / 2.5 h / Heating
4: 1) Mg turnings, 1,2-dibromoethane / 1) in THF, 6-8 h, under reflux, 2) in THF, 1 h, 20 deg C -> 1h, reflux
5: 95 percent / CrO3, conc. H2SO4 / H2O; acetone
6: 74 percent / 48percent HBr, conc. H2SO4 / 12 h / Heating
With
pyridine; chromium(VI) oxide; sodium tetrahydroborate; sulfuric acid; hydrogen bromide; phosphorus tribromide; magnesium; ethylene dibromide;
In
tetrahydrofuran; methanol; water; acetone; benzene;
DOI:10.1021/jo00188a004
