Benzeneethanol, b-(1-methylethyl)-

Base Information

• Chemical Name: Benzeneethanol, b-(1-methylethyl)-
• CAS No.: 90499-41-5
• Molecular Formula: C11H16O
• Molecular Weight: 164.247
• Mol file: 90499-41-5.mol

Synonyms:2-phenyl-3-methylbutan-1-ol;Benzeneethanol, β-(1-methylethyl)-;3-methyl-2-phenylbutan-1-ol;3-methyl-2-phenyl-butan-1-ol;3-Methyl-2-phenyl-1-butanol;γ-Methyl-β-phenyl-butylalkohol;4-Oxy-2-methyl-3-phenyl-butan;

Chemical Property of Benzeneethanol, b-(1-methylethyl)-

Chemical Property:

• Refractive Index: 1.5137 (estimate)
• Boiling Point: 251.73°C (rough estimate)
• PSA: 20.23000
• Density: 0.9694
• LogP: 2.41850

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneethanol, b-(1-methylethyl)-

There total 19 articles about Benzeneethanol, b-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-phenyl-3-methylbutyric acid methyl ester (72615-27-1) → 2-phenyl-3-methylbutanol (90499-41-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo035745c

Reference yield: 73.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + toluene-4-sulfonic acid isopropyl ester (2307-69-9) → 2-phenyl-3-methylbutanol (90499-41-5)

Guidance literature:

styrene; toluene-4-sulfonic acid isopropyl ester; With 2-cyclohexylethylmagnesium bromide; zirconocene dichloride; In tetrahydrofuran; at 55 ℃; for 12h;

With oxygen; In tetrahydrofuran; at 0 ℃; Further stages.;

DOI:10.1021/ol0160607

Reference yield: 69.0%

3-methyl-2-phenyl-1-butene (17498-71-4) → 2-phenyl-3-methylbutanol (90499-41-5)

Guidance literature:

With water; diphenyldisulfane; 9-(2-mesityl)-10-methylacridinium perchlorate; In acetonitrile; at 20 ℃; for 24h; regioselective reaction; Irradiation; Inert atmosphere;

DOI:10.1021/acscatal.6b03388

upstream raw materials:

(±)-3-methyl-2-phenylbutyramide

styrene oxide

isopropylmagnesium bromide

2-methyl-3-phenylbutane

Downstream raw materials:

acetic acid-(3-methyl-2-phenyl-butyl ester)

2-Phenyl-3-methyl-butylchlorid

(2R)-3-methyl-2-phenylbutan-1-ol

(R)-1-acetoxy-3-methyl-2-phenylbutane