1,4-Benzenediol, 2-(1,1-dimethylethyl)-, dipropanoate

Base Information

• Chemical Name: 1,4-Benzenediol, 2-(1,1-dimethylethyl)-, dipropanoate
• CAS No.: 90784-13-7
• Molecular Formula: C16H22O4
• Molecular Weight: 278.348
• Mol file: 90784-13-7.mol

Synonyms:

Chemical Property of 1,4-Benzenediol, 2-(1,1-dimethylethyl)-, dipropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-Benzenediol, 2-(1,1-dimethylethyl)-, dipropanoate

There total 2 articles about 1,4-Benzenediol, 2-(1,1-dimethylethyl)-, dipropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.2%

vinyl propionate (105-38-4) + tert-butylhydroquinone (1948-33-0) → 1-O-propanoyl-2-t-butylhydroquinone + 4-O-propanoyl-2-t-butylhydroquinone + 1,4-di-O-propanoyl-t-butylhydroquinone (90784-13-7)

Guidance literature:

With Burkholderia cepacia lipase immobilized on Celite; In tert-Amyl alcohol; cyclohexane; at 45 ℃; for 72h;

DOI:10.1016/j.tetlet.2007.10.124

Reference yield:

propionyl chloride (79-03-8) + tert-butylhydroquinone (1948-33-0) → 1,4-di-O-propanoyl-t-butylhydroquinone (90784-13-7)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/j.tetlet.2007.09.104

Reference yield: 96.8%

1,4-di-O-propanoyl-t-butylhydroquinone (90784-13-7) → 1-O-propanoyl-2-t-butylhydroquinone

Guidance literature:

With isopropyl alcohol; Candida antarctica lipase B; immobilized; In di-isopropyl ether; at 45 ℃; for 1h;

DOI:10.1016/j.tetlet.2007.09.104

upstream raw materials:

propionyl chloride

tert-butylhydroquinone

vinyl propionate

Downstream raw materials:

tert-butylhydroquinone

Refernces

• 1、 Miyazawa, Toshifumi,Hamada, Manabu,Morimoto, Ryohei,Murashima, Takashi,Yamada, Takashi. "Highly regioselective propanoylation of dihydroxybenzenes mediated by Candida antarctica lipase B in organic solvents". . p. 175 - 178. Retrieved 2008/03/30.