Oxan-4-ylazanium;chloride

Base Information

• Chemical Name: Oxan-4-ylazanium;chloride
• CAS No.: 33024-60-1
• Molecular Formula: C5H11NO^.HCl
• Molecular Weight: 137.609
• Hs Code.: 2932209090
• Mol file: 33024-60-1.mol

Synonyms:

Chemical Property of Oxan-4-ylazanium;chloride

Chemical Property:

• Vapor Pressure: 3.68mmHg at 25°C
• Melting Point: 230-250 °C
• Boiling Point: 151.4 °C at 760 mmHg
• Flash Point: 49.3 °C
• PSA: 35.25000
• LogP: 1.62640
• Storage Temp.: Keep Cold
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 137.0607417
• Heavy Atom Count: 8
• Complexity: 50

Purity/Quality:

99% ^*data from raw suppliers

4-AminotetrahydropyranHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCC1[NH3+].[Cl-]

Technology Process of Oxan-4-ylazanium;chloride

There total 9 articles about Oxan-4-ylazanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

tetrahydropyran-4-one oxime (61128-73-2) + aluminum nickel → tetrahydro-2H-pyran-4-ylamine monohydrochloride (33024-60-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; ethanol;

Reference yield:

N,N-dibenzyltetrahydro-2H-pyran-4-amine (675112-44-4) → tetrahydro-2H-pyran-4-ylamine monohydrochloride (33024-60-1)

Guidance literature:

N,N-dibenzyltetrahydro-2H-pyran-4-amine; With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 72h; under 5171.62 Torr;

With hydrogenchloride; In diethyl ether; ethanol; pH=1;

Reference yield:

Tetrahydro-4H-pyran-4-one (29943-42-8,143562-54-3) → tetrahydro-2H-pyran-4-ylamine monohydrochloride (33024-60-1)

Guidance literature:

With ammonium formate; palladium 10% on activated carbon; In methanol; water; at 20 ℃;

upstream raw materials:

N,N-dibenzyltetrahydro-2H-pyran-4-amine

Tetrahydro-4H-pyran-4-one

4-aminotetrahydropyran

tetrahydropyran-4-one oxime

Refernces

• 1、 -. "Pyrazolo[3,4-b]pyridine compounds, and their use as a PDE4 inhibitors". Page/Page column 76. . Retrieved 2009/05/28.
• 2、 -. "PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS". Page/Page column 42. . Retrieved 2008/06/13.