3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide

Base Information

Chemical Name:3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide
CAS No.:91111-99-8
Molecular Formula:C₂₃H₂₈ClN₃O₂
Molecular Weight:413.947
Hs Code.:
ChEMBL ID:CHEMBL1191673
DSSTox Substance ID:DTXSID00544217
Wikidata:Q82421268

Synonyms:91111-99-8;3-Chloro-N-(4-hydroxy-3,5-bis(pyrrolidin-1-ylmethyl)phenyl)benzamide;CHEMBL1191673;SCHEMBL10929906;DTXSID00544217;3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide

Suppliers and Price of 3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:413.1870048
Heavy Atom Count:29
Complexity:508

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CC2=CC(=CC(=C2O)CN3CCCC3)NC(=O)C4=CC(=CC=C4)Cl

Technology Process of 3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide

There total 3 articles about 3-Chloro-N-{4-hydroxy-3,5-bis[(pyrrolidin-1-yl)methyl]phenyl}benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123-30-8
4-amino-phenol

: 91111-99-8
3-Chloro-N-(4-hydroxy-3,5-bis-pyrrolidin-1-ylmethyl-phenyl)-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dioxane / 3 h

2: ethanol; H₂O / 6 h / Heating

With triethylamine; In 1,4-dioxane; ethanol; water;
DOI:10.1021/jm00376a022

Reference yield:

: 618-46-2
m-Chlorobenzoyl chloride

: 91111-99-8
3-Chloro-N-(4-hydroxy-3,5-bis-pyrrolidin-1-ylmethyl-phenyl)-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dioxane / 3 h

2: ethanol; H₂O / 6 h / Heating

With triethylamine; In 1,4-dioxane; ethanol; water;
DOI:10.1021/jm00376a022