5-Chloro-7-nitroindole-2-carboxylic acid ethyl ester

Base Information

Chemical Name:5-Chloro-7-nitroindole-2-carboxylic acid ethyl ester
CAS No.:91119-27-6
Molecular Formula:C₁₁H₉ClN₂O₄
Molecular Weight:268.656
Hs Code.:
Mol file:91119-27-6.mol

Synonyms:5-CHLORO-7-NITROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER;Ethyl 5-chloro-7-nitro-1H-indole-2-carboxylate;

Suppliers and Price of 5-Chloro-7-nitroindole-2-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
ethyl5-chloro-7-nitro-1H-indole-2-carboxylate 95
5g
$ 1750.00

Crysdot
Ethyl5-chloro-7-nitro-1H-indole-2-carboxylate 97%
1g
$ 428.00

Chemenu
Ethyl5-chloro-7-nitro-1H-indole-2-carboxylate 95%+
1g
$ 404.00

Alichem
Ethyl5-chloro-7-nitro-1H-indole-2-carboxylate
1g
$ 505.05

Alichem
Ethyl5-chloro-7-nitro-1H-indole-2-carboxylate
250mg
$ 185.64

A1 Biochem Labs
Ethyl5-chloro-7-nitro-1H-indole-2-carboxylate 95%
5 g
$ 1350.00

Total 6 raw suppliers

Chemical Property of 5-Chloro-7-nitroindole-2-carboxylic acid ethyl ester

Chemical Property:

PSA：87.91000
LogP:3.42940

Purity/Quality:

98% ^*data from raw suppliers

ethyl5-chloro-7-nitro-1H-indole-2-carboxylate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Chloro-7-nitroindole-2-carboxylic acid ethyl ester

There total 3 articles about 5-Chloro-7-nitroindole-2-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1394078-27-3
2-[(4-chloro-2-nitro-phenyl)-hydrazono]-propionic acid ethyl ester

: 91119-27-6
5-chloro-7-nitro-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: 2-[(4-chloro-2-nitro-phenyl)-hydrazono]-propionic acid ethyl ester; at 195 ℃; for 0.0833333h;

With sodium hydrogencarbonate; In water; pH=8;
DOI:10.1016/j.ejmech.2012.06.016

Reference yield:

: 54454-57-8
2-nitro-4-chlorophenylhydrazine

: 91119-27-6
5-chloro-7-nitro-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / toluene / 1 h / Reflux

2.1: polyphosphoric acid / 0.08 h / 195 °C

2.2: pH 8

With toluene-4-sulfonic acid; In toluene;
DOI:10.1016/j.ejmech.2012.06.016

Reference yield:

: 89-63-4
4-Chloro-2-nitroaniline

: 91119-27-6
5-chloro-7-nitro-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol; water / 0 - 10 °C / Industry scale

1.2: 0.5 h / -5 - 0 °C

2.1: Polyphosphoric acid (PPA) / 110 °C

With potassium hydroxide; In ethanol; water;