1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride

Base Information

Chemical Name:1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride
CAS No.:91123-65-8
Molecular Formula:C16H14ClN.ClH
Molecular Weight:292.208
Hs Code.:
DSSTox Substance ID:DTXSID90541331

Synonyms:91123-65-8;1-(CHLOROMETHYL)-4-PHENYL-3,4-DIHYDROISOQUINOLINE HCL;1-(CHLOROMETHYL)-4-PHENYL-3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE;1-(chloromethyl)-4-phenyl-3,4-dihydroisoquinoline;hydrochloride;1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline, HCl;SCHEMBL10641022;DTXSID90541331;DSJUYVRAFKJQER-UHFFFAOYSA-N;1-chloromethyl-3,4-dihydro-4-phenylisoquinoline hydrochloride;1-(chloromethyl)-4-phenyl-3,4-dihydroisoquinoline,hydrochloride;AR3737;MFCD11040497;AKOS027335017;AS-45678;A916504;1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline--hydrogen chloride (1/1);1-(CHLOROMETHYL)-4-PHENYL-3,4-DIHYDROISOQUINOLINEHYDROCHLORIDE

Suppliers and Price of 1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:291.0581549
Heavy Atom Count:19
Complexity:306

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C2=CC=CC=C2C(=N1)CCl)C3=CC=CC=C3.Cl

Technology Process of 1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride

There total 3 articles about 1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90065-24-0
N-(chloroacetyl)-2,2-diphenylethylamine

: 91123-65-8
1-(chloromethyl)-3,4-dihydro-4-phenylisoquinoline hydrochloride

Guidance literature:: With phosphorus pentoxide; In xylene; for 2h; Heating;
DOI:10.1021/jm00374a011

Reference yield:

: 3963-62-0
2,2-Diphenylethylamine

: 91123-65-8
1-(chloromethyl)-3,4-dihydro-4-phenylisoquinoline hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 122.0 g / Et₃N / CHCl₃ / 2 h / Ambient temperature

2: 88.1 g / P₂O₅ / xylene / 2 h / Heating

With phosphorus pentoxide; triethylamine; In chloroform; xylene;
DOI:10.1021/jm00374a011