2,2-Diphenylethylamine

Base Information

• Chemical Name: 2,2-Diphenylethylamine
• CAS No.: 3963-62-0
• Molecular Formula: C14H15 N
• Molecular Weight: 197.28
• Hs Code.: 29214990
• European Community (EC) Number: 223-565-7
• NSC Number: 27209
• UNII: 9XQD7X5YXD
• DSSTox Substance ID: DTXSID00192732
• Nikkaji Number: J149.896G
• Wikidata: Q61907362
• ChEMBL ID: CHEMBL10780
• Mol file: 3963-62-0.mol

Synonyms:2,2-Diphenylethylamine;2,2-Diphenylethanamine;3963-62-0;2,2-Diphenyl-ethylamine;2,2-Diphenylethan-1-Amine;1-Amino-2,2-diphenylethane;MFCD00008143;9XQD7X5YXD;CHEMBL10780;Benzeneethanamine, .beta.-phenyl-;EINECS 223-565-7;NSC-27209;NSC27209;2,2- diphenylethylamine;2,2-diphenylethyl-amine;UNII-9XQD7X5YXD;2,2-di(phenyl)ethanamine;2,2-diphenyl ethyl amine;2,2-diphenyl-ethyl-amine;beta-phenylbenzeneethanamine;2,2-Diphenylethanamine #;D0C7FL;2,2-bis-phenyl-ethylamine;Oprea1_112751;SCHEMBL149259;N-(2,2-diphenylethyl)-amine;2,2-Diphenylethylamine, 96%;BDBM35929;RXMTUVIKZRXSSM-UHFFFAOYSA-;DTXSID00192732;HMS1719E02;ETHANAMINE, 2,2-DIPHENYL-;AR3833;BBL027686;NSC 27209;STK950821;.BETA.-PHENYLBENZENEETHANAMINE;AKOS000122893;CS-W010561;NCGC00342506-01;AS-45699;BP-11477;SY050959;AM20040374;D2018;FT-0635076;EN300-13160;AB01334475-02;A824661;Z89283351

Chemical Property of 2,2-Diphenylethylamine

Chemical Property:

• Appearance/Colour: red-pink solid.
• Vapor Pressure: 0.000459mmHg at 25°C
• Melting Point: 43-49 ºC
• Refractive Index: 1.5616 (estimate)
• Boiling Point: 139-140 ºC (1.2 mmHg),314.7 °C at 760 mmHg
• PKA: 9.16±0.10(Predicted)
• Flash Point: 110 ºC
• PSA: 26.02000
• Density: 1.039 g/cm³
• LogP: 3.47750
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Methanol
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 197.120449483
• Heavy Atom Count: 15
• Complexity: 148

Purity/Quality:

97% ^*data from raw suppliers

2,2-Diphenylethylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(CN)C2=CC=CC=C2

Technology Process of 2,2-Diphenylethylamine

There total 37 articles about 2,2-Diphenylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

Diphenylacetonitrile (86-29-3) → 2,2-Diphenylethylamine (3963-62-0)

Guidance literature:

With triethylamine alane; In tetrahydrofuran; for 1h; Ambient temperature;

DOI:10.1021/jo00067a033

Reference yield: 95.0%

2,2-dimethoxyethylamine (22483-09-6) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2,2-Diphenylethylamine (3963-62-0)

Guidance literature:

With trifluorormethanesulfonic acid; at 20 ℃;

DOI:10.1021/jo0111558

Reference yield: 93.0%

Diphenylacetaldehyde (947-91-1) → 2,2-Diphenylethylamine (3963-62-0)

Guidance literature:

With nickel(II) tetrafluoroborate hexahydrate; ammonia; hydrogen; bis(2-diphenylphosphinoethyl)phenylphosphine; In 2,2,2-trifluoroethanol; at 100 ℃; for 24h; chemoselective reaction;

DOI:10.1039/d0sc01084g

upstream raw materials:

Diphenylacetonitrile

1,1'-(2-nitroethene-1,1-diyl)dibenzene

(2,2-diphenyl-ethyl)-carbamic acid ethyl ester

β,β-diphenyl-1-nitroethane

Downstream raw materials:

isonicotinic acid-(2,2-diphenyl-ethylamide)

diethyl-(2,2-diphenyl-ethyl)-amine

(2,2-diphenyl-ethyl)-isopentyl-amine; hydrochloride

N-(2,2-diphenylethyl)-N-methylamine