2-Chloro-3-(4-methoxyphenyl)-1-propene

Base Information

• Chemical Name: 2-Chloro-3-(4-methoxyphenyl)-1-propene
• CAS No.: 91284-04-7
• Molecular Formula: C10H11ClO
• Molecular Weight: 182.65
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID50448756
• Nikkaji Number: J931.269B
• Wikidata: Q82267891
• Mol file: 91284-04-7.mol

Synonyms:2-CHLORO-3-(4-METHOXYPHENYL)-1-PROPENE;91284-04-7;1-(2-chloroprop-2-enyl)-4-methoxybenzene;MFCD07698651;1-(2-Chloroprop-2-en-1-yl)-4-methoxybenzene;anisylchloroethylene;4-(2-Chloroallyl)anisole;DTXSID50448756;AKOS006284618

Chemical Property of 2-Chloro-3-(4-methoxyphenyl)-1-propene

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Boiling Point: 255.081oC at 760 mmHg
• Flash Point: 111.999oC
• PSA: 9.23000
• Density: 1.081g/cm3
• LogP: 2.99020
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 182.0498427
• Heavy Atom Count: 12
• Complexity: 148

Purity/Quality:

99% ^*data from raw suppliers

2-CHLORO-3-(4-METHOXYPHENYL)-1-PROPENE ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CC(=C)Cl

Technology Process of 2-Chloro-3-(4-methoxyphenyl)-1-propene

There total 3 articles about 2-Chloro-3-(4-methoxyphenyl)-1-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

1-bromo-4-methoxy-benzene (104-92-7) + 2,3-Dichloroprop-1-ene (78-88-6) → 1-(2-chloroprop-2-enyl)-4-methoxybenzene (91284-04-7)

Guidance literature:

1-bromo-4-methoxy-benzene; With magnesium; In tetrahydrofuran;

2,3-Dichloroprop-1-ene; With CuMe₂*SMe₂; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1016/S0040-4020(98)00681-4

Reference yield:

1-bromo-4-methoxy-benzene (104-92-7) → 1,2-propanediene (463-49-0) + 4,4'-Dimethoxybiphenyl (2132-80-1) + 1-(2-chloroprop-2-enyl)-4-methoxybenzene (91284-04-7)

Guidance literature:

With 2,3-Dichloroprop-1-ene; magnesium; Yield given. Multistep reaction; 1.) THF, 2.) THF, rt., 2 h;

DOI:10.1016/S0040-4039(00)80280-4

Reference yield:

2,3-Dichloroprop-1-ene (78-88-6) + 4-methoxybenzenediazonium tetrafluoroborate (459-64-3) → 1-(2-chloroprop-2-enyl)-4-methoxybenzene (91284-04-7) + methoxybenzene (100-66-3)

Guidance literature:

With iron(II) sulfate; In water; dimethyl sulfoxide; for 0.166667h;

DOI:10.1021/jo701717k

upstream raw materials:

1-bromo-4-methoxy-benzene

2,3-Dichloroprop-1-ene

4-methoxybenzenediazonium tetrafluoroborate

Refernces

• 1、 Hanzawa, Yuji,Kowase, Noboru,Momose, Shu-Ichi,Taguchi, Takeo. "A Cp2TiCl2-Me3Al (1:4) reagent system: An efficient reagent for generation of allylic titanocene derivatives from vinyl halides, vinyl ethers and carboxylic esters". . p. 11387 - 11398. Retrieved 2007/10/03.