5-propan-2-yl-1H-indole-2,3-dione

Base Information

• Chemical Name: 5-propan-2-yl-1H-indole-2,3-dione
• CAS No.: 150560-58-0
• Molecular Formula: C11H11 N O2
• Molecular Weight: 189.214
• Hs Code.: 2942000000
• Mol file: 150560-58-0.mol

Synonyms:5-(1-Methylethyl)-1H-indole-2,3-dione;5-Isopropylindoline-2,3-dione; 5-Isopropylisatin

Chemical Property of 5-propan-2-yl-1H-indole-2,3-dione

Chemical Property:

• Melting Point: 140 °C
• Boiling Point: °Cat760mmHg
• PKA: 9.81±0.20(Predicted)
• Flash Point: °C
• PSA: 46.17000
• Density: 1.2g/cm³
• LogP: 2.08280
• Storage Temp.: 2-8°C

Purity/Quality:

98% min ^*data from raw suppliers

5-Isopropyl-1H-indole-2,3-dione ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

Useful:

Technology Process of 5-propan-2-yl-1H-indole-2,3-dione

There total 11 articles about 5-propan-2-yl-1H-indole-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

isonitrosoaceto-p-isopropylanilide (68701-52-0) → 5-(1-Methylethyl)-1H-indole-2,3-dione (150560-58-0)

Guidance literature:

With sulfuric acid; at 20 - 30 ℃; for 2.16667h; Temperature;

Reference yield: 80.0%

C12H11N3O2 → 5-(1-Methylethyl)-1H-indole-2,3-dione (150560-58-0)

Guidance literature:

With copper(I) bromide; In water; benzonitrile; at 140 ℃; for 5h; Inert atmosphere;

DOI:10.1039/c6ra13585d

Reference yield: 75.0%

→ 5-(1-Methylethyl)-1H-indole-2,3-dione (150560-58-0)

Guidance literature:

upstream raw materials:

carbon monoxide

isonitrosoaceto-p-isopropylanilide

4-Isopropylaniline

2-bromo-4-isopropylaniline

Downstream raw materials:

3-{[4-(4-bromo-phenyl)-thiazol-2-yl]-hydrazono}-5-isopropyl-1,3-dihydro-indol-2-one

1-phenyl-5-isopropylisatin

9-isopropyl-4,5,6,7-tetraphenylazepino[3,2,1-hi]indole-1,2-dione