Technology Process of Benzene,
1,1',1''-[[3-(hexadecyloxy)-2-(phenylmethoxy)propoxy]methylidyne]tris-,
(R)-
There total 14 articles about Benzene,
1,1',1''-[[3-(hexadecyloxy)-2-(phenylmethoxy)propoxy]methylidyne]tris-,
(R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: p-TsOH / benzene / 1 h / Heating
2: 100 percent / LiAlH4, AlCl3 / 1.)ether, CH2Cl2, 25 deg C, 1 h 2.)1 h, reflux
3: 98 percent / p-TsOH / benzene
4: pyridine
5: AcOH
6: NaIO4
7: NaBH4
8: KH
With
pyridine; sodium tetrahydroborate; sodium periodate; lithium aluminium tetrahydride; aluminium trichloride; potassium hydride; toluene-4-sulfonic acid; acetic acid;
toluene-4-sulfonic acid;
In
benzene;
DOI:10.1016/S0040-4039(00)87654-6
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 95 percent / LiAlH4-AlCl3 / CH2Cl2; diethyl ether / 1 h / Heating
2: 1.) triethylorthoformate, p-TsOH / 1.) toluene, room temp., 2h; 2.) room temp., 24 h
3: 74 percent / 4,4-dimethylaminopyridine / pyridine / 50 °C
4: 90 percent / acetic acid / ethanol / 48 h / Ambient temperature
5: 1.) NaIO4; 2.) NaBH4 / 1.) 90percent aqueous methanol, 0 deg C, 2 h; 2.) 0 deg C, 2 h
6: 85 percent / KH (22percent) / benzene / Heating
With
dmap; sodium tetrahydroborate; sodium periodate; lithium aluminium tetrahydride; aluminium trichloride; potassium hydride; toluene-4-sulfonic acid; acetic acid; orthoformic acid triethyl ester;
In
pyridine; diethyl ether; ethanol; dichloromethane; benzene;
DOI:10.1248/cpb.33.572
