2-Propenoic acid, 3-phenyl-, 2-propynyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 3-phenyl-, 2-propynyl ester
• CAS No.: 91368-35-3
• Molecular Formula: C12H10O2
• Molecular Weight: 186.21
• Mol file: 91368-35-3.mol

Synonyms:propargyl cinnamate;2-Propenoic acid,3-phenyl-,2-propynyl ester;trans-Zimtsaeure-3-propargylester;prop-2-ynyl cinnamate;trans-Zimtsaeure-propargylester;prop-2-ynyl 3-phenylacrylate;(E)-prop-2-ynyl cinnamate;

Chemical Property of 2-Propenoic acid, 3-phenyl-, 2-propynyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 1.87620

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 3-phenyl-, 2-propynyl ester

There total 8 articles about 2-Propenoic acid, 3-phenyl-, 2-propynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

propargyl alcohol (107-19-7) + Cinnamic acid (621-82-9) → prop-2-yn-1-yl cinnamate (91368-35-3)

Guidance literature:

With pyridine;

DOI:10.1016/j.bmcl.2008.12.108

Reference yield: 93.0%

(E)-3-phenylacrylic acid (140-10-3) + propargyl bromide (106-96-7) → prop-2-ynyl 3-phenylacrylate (91368-35-3,29584-63-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; toluene; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.ejmech.2021.113687

Reference yield: 89.0%

(E)-3-phenylacrylic acid (140-10-3) + propargyl alcohol (107-19-7) → prop-2-ynyl 3-phenylacrylate (91368-35-3,29584-63-2)

Guidance literature:

With silica gel-immobilized perchloric acid; at 80 ℃; for 7h; Inert atmosphere; Neat (no solvent);

DOI:10.1021/jo900614s

upstream raw materials:

propargyl alcohol

Cinnamoyl chloride

(E)-3-phenylacrylic acid

α-bromocinnamaldehyde

Downstream raw materials:

3-(trimethylsilyl)prop-2-ynyl cinnamate