Propanamide, 2-(4-chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methyl-

Base Information

• Chemical Name: Propanamide, 2-(4-chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methyl-
• CAS No.: 124237-33-8
• Molecular Formula: C₁₇H₂₁ClN₂O₂
• Molecular Weight: 320.819
• DSSTox Substance ID: DTXSID80154252
• Wikidata: Q83021408
• Mol file: 124237-33-8.mol

Synonyms:BRN 4516625;Propanamide, 2-(4-chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methyl-;2-(4-Chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methylpropanamide;124237-33-8;DTXSID80154252;LS-119089

Chemical Property of Propanamide, 2-(4-chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methyl-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.15g/cm³
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 320.1291556
• Heavy Atom Count: 22
• Complexity: 392

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(N1NC(=O)C(C)(C)OC2=CC(=C(C=C2)Cl)C)C

Technology Process of Propanamide, 2-(4-chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methyl-

There total 3 articles about Propanamide, 2-(4-chloro-3-methylphenoxy)-N-(2,5-dimethyl-1H-pyrrol-1-yl)-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

α-(3-methyl-4-chlorophenoxy) isobutyric acid hydrazide (78613-32-8) + 2,5-hexanedione (110-13-4) → 1-(4'-chloro-3'-methylphenoxyisobutyramido)-2,5-dimethylpyrrole (124237-33-8)

Guidance literature:

With acetic acid; Heating;

Reference yield:

4-Chloro-3-methylphenol (59-50-7) → 1-(4'-chloro-3'-methylphenoxyisobutyramido)-2,5-dimethylpyrrole (124237-33-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / sodium hydroxide / Heating

2: 96 percent / hydrazine hydrate / ethanol / Heating

3: 92 percent / acetic acid / Heating

With sodium hydroxide; hydrazine hydrate; acetic acid; In ethanol;

Reference yield:

α-(3-methyl-4-chlorophenoxy)isobutyric acid (62443-89-4) → 1-(4'-chloro-3'-methylphenoxyisobutyramido)-2,5-dimethylpyrrole (124237-33-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / hydrazine hydrate / ethanol / Heating

2: 92 percent / acetic acid / Heating

With hydrazine hydrate; acetic acid; In ethanol;

upstream raw materials:

α-(3-methyl-4-chlorophenoxy) isobutyric acid hydrazide

2,5-hexanedione

4-Chloro-3-methylphenol

α-(3-methyl-4-chlorophenoxy)isobutyric acid