Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl-, hydrazide

Base Information

• Chemical Name: Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl-, hydrazide
• CAS No.: 78613-32-8
• Molecular Formula: C11H15ClN2O2
• Molecular Weight: 242.702
• DSSTox Substance ID: DTXSID20229216
• Wikidata: Q83109428
• Mol file: 78613-32-8.mol

Synonyms:BRN 4682703;Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl-, hydrazide;78613-32-8;2-(4-Chloro-3-methylphenoxy)-2-methylpropanoic acid hydrazide;2-(4-chloro-3-methylphenoxy)-2-methylpropanehydrazide;Oprea1_299576;DTXSID20229216;STK435802;AKOS003331433;LS-121272

Chemical Property of Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl-, hydrazide

Chemical Property:

• Vapor Pressure: 1.05E-07mmHg at 25°C
• Boiling Point: 433.1°Cat760mmHg
• Flash Point: 215.7°C
• Density: 1.208g/cm³
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 242.0822054
• Heavy Atom Count: 16
• Complexity: 258

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)OC(C)(C)C(=O)NN)Cl

Technology Process of Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl-, hydrazide

There total 2 articles about Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

α-(3-methyl-4-chlorophenoxy)isobutyric acid (62443-89-4) → α-(3-methyl-4-chlorophenoxy) isobutyric acid hydrazide (78613-32-8)

Guidance literature:

With hydrazine hydrate; In ethanol; Heating;

Reference yield:

4-Chloro-3-methylphenol (59-50-7) → α-(3-methyl-4-chlorophenoxy) isobutyric acid hydrazide (78613-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / sodium hydroxide / Heating

2: 96 percent / hydrazine hydrate / ethanol / Heating

With sodium hydroxide; hydrazine hydrate; In ethanol;

Reference yield: 98.0%

bromocyane (506-68-3) + α-(3-methyl-4-chlorophenoxy) isobutyric acid hydrazide (78613-32-8) → 2-amino-5-<α-(3'-methyl-4'-chlorophenoxy) isopropyl>-1,3,4-oxadiazole (78613-27-1)

Guidance literature:

upstream raw materials:

α-(3-methyl-4-chlorophenoxy)isobutyric acid

4-Chloro-3-methylphenol

Downstream raw materials:

2-amino-5-<α-(3'-methyl-4'-chlorophenoxy) isopropyl>-1,3,4-oxadiazole

1-(4'-chloro-3'-methylphenoxyisobutyramido)-2,5-dimethylpyrrole