1-(3-Methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol

Base Information

Chemical Name:1-(3-Methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol
CAS No.:66307-45-7
Molecular Formula:C20H26N2O3
Molecular Weight:342.432
Hs Code.:
NSC Number:91378
Nikkaji Number:J117.865B
ChEMBL ID:CHEMBL1491813

Synonyms:66307-45-7;1-(3-methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol;MLS000736915;.alpha.-[m-(Methoxyphenoxy)methyl]-4-phenyl-1-piperazineethanol;NSC91378;alpha-(m-Methoxyphenoxymethyl)-4-phenyl-1-piperazineethanol;1-Piperazineethanol, alpha-(m-methoxyphenoxymethyl)-4-phenyl-;NCIOpen2_009830;Oprea1_134269;CHEMBL1491813;1-(3-methoxyphenoxy)-3-(4-phenyl-1-piperazinyl)-2-propanol;HMS2884N15;1-Piperazineethanol, .alpha.-[(3-methoxyphenoxy)methyl]-4-phenyl-;NSC 91378;NSC-91378;AKOS001634611;AKOS016287017;NCGC00245851-01;NCGC00245851-02;SMR000528423;EU-0006347;AF-399/37321001;1-Piperazineethanol, .alpha.-[m-(methoxyphenoxy)methyl]-4-phenyl-

Suppliers and Price of 1-(3-Methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(3-Methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol

Chemical Property:

Vapor Pressure:5.63E-12mmHg at 25°C
Boiling Point:528°Cat760mmHg
Flash Point:273.1°C
PSA：45.17000
Density:1.152g/cm³
LogP:2.26000
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:342.19434270
Heavy Atom Count:25
Complexity:368

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC=C1)OCC(CN2CCN(CC2)C3=CC=CC=C3)O

Technology Process of 1-(3-Methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol

There total 3 articles about 1-(3-Methoxyphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 150-19-6
O-methylresorcine

: 66307-45-7
1-(3-methoxy-phenoxy)-3-(4-phenyl-piperazin-1-yl)-propan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: (CF₃)3COH / chiral polymer-supported Co(salen) complex / 6 h / 4 - 25 °C

1.2: KOH / diethyl ether / 3 h / 25 °C

2.1: Yb(OTf)3 / CH₂Cl₂ / 16 h / 25 °C

With 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-ol; ytterbium(III) triflate; chiral polymer-supported Co(salen) complex; In dichloromethane;
DOI:10.1021/ol990920q