2-(9-Methoxy-9H-fluoren-9-YL)-3,5-dimethylaniline

Base Information

• Chemical Name: 2-(9-Methoxy-9H-fluoren-9-YL)-3,5-dimethylaniline
• CAS No.: 91481-73-1
• Molecular Formula: C₂₂H₂₁NO
• Molecular Weight: 315.415
• DSSTox Substance ID: DTXSID50543230
• Wikidata: Q82420065
• Mol file: 91481-73-1.mol

Synonyms:91481-73-1;2-(9-METHOXY-9H-FLUOREN-9-YL)-3,5-DIMETHYLANILINE;DTXSID50543230

Chemical Property of 2-(9-Methoxy-9H-fluoren-9-YL)-3,5-dimethylaniline

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 315.162314293
• Heavy Atom Count: 24
• Complexity: 427

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)N)C2(C3=CC=CC=C3C4=CC=CC=C42)OC)C

Technology Process of 2-(9-Methoxy-9H-fluoren-9-YL)-3,5-dimethylaniline

There total 2 articles about 2-(9-Methoxy-9H-fluoren-9-YL)-3,5-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

methanol (67-56-1) + ap-9-(2-azido-4,6-dimethylphenyl)fluorene (85681-33-0) → 9-methoxy-9-(2-amino-4,6-dimethylphenyl)fluorene (91481-73-1) + 3,5-dimethyl-4b-aza-7H-benzindenoazulene (98128-24-6) + 4,6-dimethyl-7-(9-fluorenyl)-2-methoxy-3H-azepine (98128-23-5)

Guidance literature:

With sodium methylate; In diethyl ether; at 27 ℃; Product distribution; Irradiation; effect of starting rotamer, variuos temperature, effect of concentration of added base;

DOI:10.1021/ja00308a027

Reference yield:

methanol (67-56-1) + 6-Fluoren-9-ylidene-3,5-dimethyl-cyclohexa-2,4-dienylideneamine (85681-36-3) → 9-methoxy-9-(2-amino-4,6-dimethylphenyl)fluorene (91481-73-1)

Guidance literature:

In diethyl ether; at 25 ℃; Mechanism; Rate constant; Irradiation;

DOI:10.1016/S0040-4039(01)90079-6

upstream raw materials:

methanol

6-Fluoren-9-ylidene-3,5-dimethyl-cyclohexa-2,4-dienylideneamine

ap-9-(2-azido-4,6-dimethylphenyl)fluorene