1’-Oxo Perazine

Base Information

• Chemical Name: 1’-Oxo Perazine
• CAS No.: 91508-47-3
• Molecular Formula: C20H23N3OS
• Molecular Weight: 353.488
• Mol file: 91508-47-3.mol

Synonyms:1'-Oxo Perazine;

Chemical Property of 1’-Oxo Perazine

Chemical Property:

• PSA: 52.09000
• LogP: 3.39420
• Solubility.: Dichloromethane, Methanol

Purity/Quality:

97% ^*data from raw suppliers

1’-OxoPerazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Perazine intermediate.

Technology Process of 1’-Oxo Perazine

There total 4 articles about 1’-Oxo Perazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-methyl-piperazine (109-01-3) + 10H-phenothiazine-10-propanoyl chloride (89755-05-5) → β-(10-phenothiazinyl)propion-4-methylpiperazide (91508-47-3)

Guidance literature:

In benzene; for 0.5h;

Reference yield: 73.0%

1-methyl-piperazine (109-01-3) + methyl β-(10-phenothiazinyl)propionate (362-04-9) → β-(10-phenothiazinyl)propion-4-methylpiperazide (91508-47-3)

Guidance literature:

at 132 - 135 ℃;

Reference yield:

10H-phenothiazine-10-propanenitrile (1698-80-2) → β-(10-phenothiazinyl)propion-4-methylpiperazide (91508-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus pentachloride / benzene / 1 h / 5 - 20 °C

2: 89 percent / benzene / 0.5 h

With phosphorus pentachloride; In benzene;

upstream raw materials:

1-methyl-piperazine

10H-phenothiazine-10-propanoyl chloride

methyl β-(10-phenothiazinyl)propionate

10H-phenothiazine

Downstream raw materials:

Perazin

3-(10H-phenothiazin-10-yl)propan-1-ol

Refernces

• 1、 Owen, Terence C.. "Synthesis of Perazine". . p. 265 - 266. Retrieved 2007/10/02.