4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

Base Information

Chemical Name:4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol
CAS No.:108957-72-8
Molecular Formula:C17H18O4
Molecular Weight:286.328
Hs Code.:2909500000
NSC Number:381281
Nikkaji Number:J2.114.042B,J656.391K
Pharos Ligand ID:ULPZ6Q9XH3M5
Metabolomics Workbench ID:122700
ChEMBL ID:CHEMBL119576
Mol file:108957-72-8.mol

Synonyms:3,3',5'-tri-O-methylpiceatannol;NSC 381281;NSC-381281

Suppliers and Price of 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(E) -4'-HYDROXY-3,5,3'-TRIMETHOXYSTILBENE 95.00%
5G
$ 909.56

Total 18 raw suppliers

Chemical Property of 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

Chemical Property:

Appearance/Colour:White, off grey crystal powder
Vapor Pressure:1.36E-08mmHg at 25°C
Refractive Index:1.621
Boiling Point:446.7 °C at 760 mmHg
Flash Point:223.9 °C
PSA：47.92000
Density:1.177 g/cm³
LogP:3.58840
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:286.12050905
Heavy Atom Count:21
Complexity:319

Purity/Quality:

99%, ^*data from raw suppliers

(E) -4'-HYDROXY-3,5,3'-TRIMETHOXYSTILBENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1)C=CC2=CC(=C(C=C2)O)OC)OC
Isomeric SMILES:COC1=CC(=CC(=C1)/C=C/C2=CC(=C(C=C2)O)OC)OC

Technology Process of 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

There total 6 articles about 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: trans-3,3',5-trimethoxy-4'-tert-butyldimethylsilyloxystilbene

: 108957-72-8
(trans)-4-[2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 0.75h;
DOI:10.1021/jm030785u

Reference yield: 45.0%

: 54922-76-8
(E)-1-(benzyloxy)-4-(3,5-dimethoxystyryl)-2-methoxybenzene

: 108957-72-8
(trans)-4-[2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

Guidance literature:: With boron tribromide; isoascorbic acid; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;
DOI:10.5012/bkcs.2010.31.04.971

Reference yield:

: 69404-94-0
O-tert-butyldimethylsilylvanillin

: 108957-72-8
(trans)-4-[2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxyphenol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 °C

1.2: 35 percent / tetrahydrofuran; hexane / 20 °C

2.1: 88 percent / TBAF / tetrahydrofuran / 0.75 h

With n-butyllithium; tetrabutyl ammonium fluoride; In tetrahydrofuran; hexane;
DOI:10.1021/jm030785u