69404-94-0

Basic information

• Product Name: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-
• CAS NO: 69404-94-0
• Molecular Formula: C14H22O3Si
• Molecular Weight: 266.412
• Mol File: 69404-94-0.mol
• Article Data: 47

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-(69404-94-0)
• EPA Substance Registry System: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxy-(69404-94-0)

Safety Data

• Hazardous Substances Data: 69404-94-0(Hazardous Substances Data)

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 121-33-5 vanillin 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 33284-74-1 brittonin A 
• 113932-00-6 1-[4-(tert-Butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-(3,4,5-trimethoxy-phenyl)-ethanol 
• 113932-01-7 isocombretastatin C 
• 132255-78-8 4-(tert.-Butyldimethylsilyloxy)-3-methoxyacetophenon 
• 882304-30-5 3-(4-methylsulfanylphenyl)-1-[4-(tert-butyldimethylsilyloxy)-3-methoxyphenyl]prop-2-yn-1-ol 
• 252679-49-5 2-methoxy-4-((E)-4-(2(E)-3,7-dimethyl-2,6-octadienyl)-3,5-bis(methoxymethoxy)phenylethenyl)phenol 
• 252679-46-2 tert-butyldimethylsilyloxy-4-((E)-4-((2E)-3,7-dimethyl-2,6-octadienyl)-3,5-bis(methoxymethoxy)phenylethenyl)-2-methoxybenzene 
• 3391-75-1 2-methoxy-4-((E)-phenylethenyl)phenol 
• 252679-41-7 tert-butyldimethylsilyloxy-2-methoxy-4-((E)-phenylethenyl)benzene 
• 121-33-5 vanillin 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 60632-40-8 6-bromovanillin 
• 842150-42-9 tert-butyl-(4-[1,3]dioxan-2-yl-2-methoxyphenoxy)dimethylsilane 
• 951795-32-7 (4-t-butyldimethylsilanyloxy-3-methoxyphenyl)-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenylamino]acetonitrile 

Relevant articles and documents

Chromium-Salen Complex/Nitroxyl Radical Cooperative Catalysis: A Combination for Aerobic Intramolecular Dearomative Coupling of Phenols

We describe an aerobic intramolecular dearomative coupling reaction of tethered phenols using a catalytic system consisting of a chromium-salen (Cr-salen) complex combined with a nitroxyl radical. This novel catalytic system enables formation of various spirocyclic dienone products including those unable to be accessed by previously reported methods efficiently under mild reaction conditions.

Synthesis method of yakuchinone-A

The invention provides a synthesis method of yakuchinone-A, and belongs to the technical field of organic chemical synthesis. The preparation method is suitable for industrial production of the yakuchinone-A. According to the method, vanillin is taken as a starting raw material, an alkylation reaction, a wittig-harner reaction, a hydrolysis reaction, a reduction reaction and various reactions are sequentially carried out to finally obtain crude yakuchinone, and then the crude yakuchinone is recrystallized by an organic solvent to prepare the high-purity yakuchinone. The method specifically characterized by synthesizing a compound 8 through the vanillin, synthesizing a compound 9 through the compound 8, synthesizing a compound 10 through the compound 9, synthesizing a compound 11 through the compound 10, and finally synthesizing the yakuchinone-A through the compound 11, and then obtaining the high-purity yakuchinone-A through a recrystallization means. The synthesis method disclosed by the invention has the advantages of easily available raw materials, low cost, easiness in operation, good safety, less pollution, simplicity in purification, easiness in quality control and the like.

PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS

Photoactive probes and probe systems for detecting biological interactions are described. The photoactive probes include probes that combine both photocleavable and photoreactive moieties. The photoactive probe systems can include a first probe comprising a photocatalytic group and a second probe comprising a group that can act as a substrate for the reaction catalyzed by the photocatalytic group. The probes and probe systems can also include groups that can specifically bind to a binding partner on a biological entity of interest and a detectable group or a precursor thereof. The probes and probe systems can detect spatiotemporal interactions of proteins or cells. In some embodiments, the interactions can be detected in live cells. Also described are methods of detecting the biological interactions.